KEGG   Homo sapiens (human): 22848
Entry
22848             CDS       T01001                                 
Symbol
AAK1
Name
(RefSeq) AP2 associated kinase 1
  KO
K08853  AP2-associated kinase [EC:2.7.11.1]
Organism
hsa  Homo sapiens (human)
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:hsa01001]
    22848 (AAK1)
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:hsa04131]
    22848 (AAK1)
Enzymes [BR:hsa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     22848 (AAK1)
Protein kinases [BR:hsa01001]
 Serine/threonine kinases: Other
  NAK family [OT]
   22848 (AAK1)
Membrane trafficking [BR:hsa04131]
 Endocytosis
  Clathrin-mediated endocytosis
   Kinases
    22848 (AAK1)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kinase-like Pkinase_fungal Kdo ABC1 APH Haspin_kinase
Other DBs
NCBI-GeneID: 22848
NCBI-ProteinID: NP_055726
OMIM: 616405
HGNC: 19679
Ensembl: ENSG00000115977
UniProt: Q2M2I8
Structure
Position
2:complement(69457997..69643739)
AA seq 961 aa
MKKFFDSRREQGGSGLGSGSSGGGGSTSGLGSGYIGRVFGIGRQQVTVDEVLAEGGFAIV
FLVRTSNGMKCALKRMFVNNEHDLQVCKREIQIMRDLSGHKNIVGYIDSSINNVSSGDVW
EVLILMDFCRGGQVVNLMNQRLQTGFTENEVLQIFCDTCEAVARLHQCKTPIIHRDLKVE
NILLHDRGHYVLCDFGSATNKFQNPQTEGVNAVEDEIKKYTTLSYRAPEMVNLYSGKIIT
TKADIWALGCLLYKLCYFTLPFGESQVAICDGNFTIPDNSRYSQDMHCLIRYMLEPDPDK
RPDIYQVSYFSFKLLKKECPIPNVQNSPIPAKLPEPVKASEAAAKKTQPKARLTDPIPTT
ETSIAPRQRPKAGQTQPNPGILPIQPALTPRKRATVQPPPQAAGSSNQPGLLASVPQPKP
QAPPSQPLPQTQAKQPQAPPTPQQTPSTQAQGLPAQAQATPQHQQQLFLKQQQQQQQPPP
AQQQPAGTFYQQQQAQTQQFQAVHPATQKPAIAQFPVVSQGGSQQQLMQNFYQQQQQQQQ
QQQQQQLATALHQQQLMTQQAALQQKPTMAAGQQPQPQPAAAPQPAPAQEPAIQAPVRQQ
PKVQTTPPPAVQGQKVGSLTPPSSPKTQRAGHRRILSDVTHSAVFGVPASKSTQLLQAAA
AEASLNKSKSATTTPSGSPRTSQQNVYNPSEGSTWNPFDDDNFSKLTAEELLNKDFAKLG
EGKHPEKLGGSAESLIPGFQSTQGDAFATTSFSAGTAEKRKGGQTVDSGLPLLSVSDPFI
PLQVPDAPEKLIEGLKSPDTSLLLPDLLPMTDPFGSTSDAVIEKADVAVESLIPGLEPPV
PQRLPSQTESVTSNRTDSLTGEDSLLDCSLLSNPTTDLLEEFAPTAISAPVHKAAEDSNL
ISGFDVPEGSDKVAEDEFDPIPVLITKNPQGGHSRNSSGSSESSLPNLARSLLLVDQLID
L
NT seq 2886 nt   +upstreamnt  +downstreamnt
atgaagaagtttttcgactcccggcgagagcagggcggctctggcctgggctccggctcc
agcggaggagggggcagcacctcgggcctgggcagtggctacatcggaagagtcttcggc
atcgggcgacagcaggtcacagtggacgaggtgttggcggaaggtggatttgctattgta
tttctggtgaggacaagcaatgggatgaaatgtgccttgaaacgcatgtttgtcaacaat
gagcatgatctccaggtgtgcaagagagaaatccagataatgagggatctttcagggcac
aagaatattgtgggttacattgattctagtatcaacaacgtgagtagcggtgatgtatgg
gaagtgctcattctgatggacttttgtagaggtggccaggtggtaaacctgatgaaccag
cgcctgcaaacaggctttacagagaatgaagtgctccagatattttgtgatacctgtgaa
gctgttgcccgcctgcatcagtgcaaaactcctattatccaccgggacctgaaggttgaa
aacatcctcttgcatgaccgaggccactatgtcctgtgtgactttggaagcgccaccaac
aaattccagaatccacaaactgagggagtcaatgcagtagaagatgagattaagaaatac
acaacgctgtcctatcgagcaccagaaatggtcaacctgtacagtggcaaaatcatcact
acgaaggcagacatttgggctcttggatgtttgttgtataaattatgctacttcactttg
ccatttggggaaagtcaggtggcaatttgtgatggaaacttcacaattcctgataattct
cgatattctcaagacatgcactgcctaattaggtatatgttggaaccagaccctgacaaa
aggccggatatttaccaggtgtcctacttctcatttaagctactcaagaaagagtgccca
attccaaatgtacagaactctcccattcctgcaaagcttcctgaaccagtgaaagccagt
gaggcagctgcaaaaaagacccagccaaaggccagactgacagatcccattcccaccaca
gagacttcaattgcaccccgccagaggcctaaagctgggcagactcagccgaacccagga
atccttcccatccagccagcgctgacaccccggaagagggccactgttcagcccccacct
caggctgcaggatccagcaatcagcctggccttttagccagtgttccccaaccaaaaccc
caagccccacccagccagcctctgccgcaaactcaggccaagcagccacaggctcctccc
actccacagcagacgccttctactcaggcccagggtctgcccgctcaggcccaggccaca
ccccagcaccagcagcaactcttcctcaagcagcaacagcagcagcaacagccaccgcca
gcacagcagcagccggcaggcacgttttaccagcagcagcaggcccagactcagcagttt
caggcagtacatccagcaacccagaaaccagcaattgctcagttccctgtggtgtcccaa
ggaggctctcaacagcagctaatgcagaatttctaccagcagcagcagcagcagcaacaa
caacagcaacagcaacagctggccacagccctgcatcaacaacagctgatgactcagcag
gctgccttgcagcaaaagcccactatggcagcaggacagcagccccagccacagccagct
gcagccccacagccagcccctgcccaggagccagcgattcaagccccagtaagacaacag
ccaaaggttcagacaaccccacctcctgccgtccaggggcagaaagttggatctctcact
ccaccctcatcccccaaaacccaacgtgctgggcacaggcgtattctcagtgacgtaacc
cacagtgcagtctttggggtccctgccagcaaatcaacccagctgctccaggcagctgca
gctgaggccagtctcaataagtccaagtctgcaaccaccactccatcaggctctcctcgg
acctctcaacaaaacgtttataatccttcagaagggtctacgtggaatccctttgatgac
gataatttctccaaactcacagctgaagaactgctaaacaaggactttgccaagcttggg
gaaggcaaacatcccgagaagcttggaggctcagctgagagtttgatcccaggctttcaa
tcaacccaaggtgatgcttttgctacgacctcattttctgctggaactgctgaaaaaagg
aagggtgggcagactgtggactctggcctcccgcttctaagcgtgtctgatcctttcatt
cctcttcaagtacctgatgcaccagaaaaactaattgagggactcaaatctcctgacact
tctcttctgctccctgacctcttgcctatgacagatccttttggtagcacttctgatgct
gtaattgaaaaagctgatgttgctgttgagagtctcataccaggactggagcccccagtt
ccccagcgcctcccatctcagacggaatctgtgacctcgaatcgcacagattctctcacc
ggggaagattccctgcttgattgctctctgctctctaaccctactactgaccttctggaa
gagtttgcccccacagcaatctctgctccagtccataaagctgcagaagatagtaatctc
atctcaggttttgatgtccctgagggctcggacaaggtggctgaagatgagtttgaccct
attcctgtattgataaccaaaaacccacaaggtgggcactctagaaacagcagtgggagc
tctgagtccagtcttcccaacctagccaggtctttactgctggtggatcagctcatagac
ctgtag

  All links  
Ontology (4)   
   KEGG BRITE (4)   
Disease (1)   
   OMIM (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (17)   
   KEGG ORTHOLOGY (1)   
   RefGene (10)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
Protein sequence (7)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (5)   
DNA sequence (55)   
   RefSeq(nuc) (5)   
   GenBank (25)   
   EMBL (25)   
3D Structure (5)   
   PDB (5)   
Protein domain (8)   
   Pfam (8)   
All databases (99)   

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