KEGG   Mus musculus (house mouse): 11479
Entry
11479             CDS       T01002                                 
Symbol
Acvr1b, 6820432J04, ALK-4, ActR-IB, ActRIB, Acvrlk4, Alk4, SKR2
Name
(RefSeq) activin A receptor, type 1B
  KO
K13567  activin receptor type-1B [EC:2.7.11.30]
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu04060  Cytokine-cytokine receptor interaction
mmu04350  TGF-beta signaling pathway
mmu04550  Signaling pathways regulating pluripotency of stem cells
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04350 TGF-beta signaling pathway
    11479 (Acvr1b)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    11479 (Acvr1b)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    11479 (Acvr1b)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:mmu01001]
    11479 (Acvr1b)
Enzymes [BR:mmu01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.30  receptor protein serine/threonine kinase
     11479 (Acvr1b)
Protein kinases [BR:mmu01001]
 Receptor serine/threonine kinases (RSTK): TKL group
  TGFBR1 family [OT]
   11479 (Acvr1b)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr TGF_beta_GS Activin_recp APH Pkinase_fungal FTA2
Other DBs
NCBI-GeneID: 11479
NCBI-ProteinID: NP_031421
MGI: 1338944
Ensembl: ENSMUSG00000000532
UniProt: Q61271 Q3TZF1
Position
15:101071953..101111565
AA seq 505 aa
MAESAGASSFFPLVVLLLAGSGGSGPRGIQALLCACTSCLQTNYTCETDGACMVSIFNLD
GVEHHVRTCIPKVELVPAGKPFYCLSSEDLRNTHCCYIDFCNKIDLRVPSGHLKEPAHPS
MWGPVELVGIIAGPVFLLFLIIIIVFLVINYHQRVYHNRQRLDMEDPSCEMCLSKDKTLQ
DLVYDLSTSGSGSGLPLFVQRTVARTIVLQEIIGKGRFGEVWRGRWRGGDVAVKIFSSRE
ERSWFREAEIYQTVMLRHENILGFIAADNKDNGTWTQLWLVSDYHEHGSLFDYLNRYTVT
IEGMIKLALSAASGLAHLHMEIVGTQGKPGIAHRDLKSKNILVKKNGMCAIADLGLAVRH
DAVTDTIDIAPNQRVGTKRYMAPEVLDETINMKHFDSFKCADIYALGLVYWEIARRCNSG
GVHEDYQLPYYDLVPSDPSIEEMRKVVCDQKLRPNVPNWWQSYEALRVMGKMMRECWYAN
GAARLTALRIKKTLSQLSVQEDVKI
NT seq 1518 nt   +upstreamnt  +downstreamnt
atggcggagtcggccggagcctcctccttcttcccccttgttgtcctcctgctcgccggc
agcggcgggtccgggccccgggggatccaggctctgctgtgtgcgtgcaccagctgccta
cagaccaactacacctgtgagacagatggggcttgcatggtctccatctttaacctggat
ggcgtggagcaccatgtacgtacctgcatccccaaggtggagctggttcctgctggaaag
cccttctactgcctgagttcagaggatctgcgcaacacacactgctgctatattgacttc
tgcaacaagattgacctcagggtccccagcggacacctcaaggagcctgcgcacccctcc
atgtggggccctgtggagctggtcggcatcatcgccggccccgtcttcctcctcttcctt
atcattatcatcgtcttcctggtcatcaactatcaccagcgtgtctaccataaccgccag
aggttggacatggaggacccctcttgcgagatgtgtctctccaaagacaagacgctccag
gatctcgtctacgacctctccacgtcagggtctggctcagggttacccctttttgtccag
cgcacagtggcccgaaccattgttttacaagagattatcggcaagggccggttcggggaa
gtatggcgtggtcgctggaggggtggtgacgtggctgtgaaaatcttctcttctcgtgaa
gaacggtcttggttccgtgaagcagagatctaccagaccgtcatgctgcgccatgaaaac
atccttggctttattgctgctgacaataaagataatggcacctggacccagctgtggctt
gtctctgactatcacgagcatggctcactgtttgattatctgaaccgctacacagtgacc
attgagggaatgattaagctagccttgtctgcagccagtggtttggcacacctgcatatg
gagattgtgggcactcaagggaagccgggaattgctcatcgagacttgaagtcaaagaac
atcctggtgaaaaaaaatggcatgtgtgccattgcagacctgggcctggctgtccgtcat
gatgcggtcactgacaccatagacattgctccaaatcagagggtggggaccaaacgatac
atggctcctgaagtccttgacgagacaatcaacatgaagcactttgactccttcaaatgt
gccgacatctatgccctcgggcttgtctactgggagattgcacgaagatgcaattctgga
ggagtccatgaagactatcaactgccgtattacgacttagtgccctccgacccttccatt
gaggagatgcgaaaggttgtatgtgaccagaagctacggcccaatgtccccaactggtgg
cagagttatgaggccttgcgagtgatgggaaagatgatgcgggagtgctggtacgccaat
ggtgctgcccgtctgacagctctgcgcatcaagaagactctgtcccagctaagcgtgcag
gaagatgtgaagatttaa

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (3)   
   KEGG PATHWAY (3)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (13)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
   RefGene (6)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
Protein sequence (4)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (15)   
   RefSeq(nuc) (1)   
   GenBank (7)   
   EMBL (7)   
Protein domain (7)   
   Pfam (7)   
All databases (47)   

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