| Entry |
|
|---|
| Name |
Galanthamine;
Galantamine
|
|---|
| Formula |
C17H21NO3
|
|---|
| Exact mass |
287.1521
|
|---|
| Mol weight |
287.3535
|
|---|
| Structure |
|
|---|
| Remark |
|
|---|
| Reaction |
|
|---|
| Pathway |
| map00950 | Isoquinoline alkaloid biosynthesis |
| map01063 | Biosynthesis of alkaloids derived from shikimate pathway |
| map01110 | Biosynthesis of secondary metabolites |
|
|---|
| Enzyme |
2.1.1.-
|
|---|
| Brite |
Phytochemical compounds [BR:br08003]
Alkaloids
Alkaloids derived from tyrosine
Isoquinoline alkaloids
C08526 Galanthamine
Natural toxins [BR:br08009]
Phytotoxins
Alkaloids
Isoquinoline alkaloids
C08526 Galanthamine
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
N NERVOUS SYSTEM
N06 PSYCHOANALEPTICS
N06D ANTI-DEMENTIA DRUGS
N06DA Anticholinesterases
N06DA04 Galantamine
D04292 Galantamine (USAN/INN)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01595 Cholinesterase inhibitor
DG01593 Acetylcholinesterase inhibitor
DG00985 Galantamine
D04292 Galantamine
DG01968 Antidementia agent
DG00985 Galantamine
D04292 Galantamine
Metabolizing enzyme substrate
DG01644 CYP2D6 substrate
DG00985 Galantamine
D04292 Galantamine
DG01633 CYP3A/CYP3A4 substrate
DG02913 CYP3A4 substrate
DG00985 Galantamine
D04292 Galantamine
Target-based classification of drugs [BR:br08310]
Enzymes
Hydrolases (EC3)
Carboxylic-ester hydrolases
ACHE
D04292 Galantamine (USAN/INN)
Drug metabolizing enzymes and transporters [br08309.html]
Drug metabolizing enzymes
D04292
|
|---|
| Other DBs |
|
|---|
| KCF data |
ATOM 21
1 C8y C 23.0362 -23.9428
2 C1x C 24.0864 -24.7130
3 N1y N 25.4167 -24.4329
4 C1x C 25.9769 -23.1727
5 C8y C 23.0362 -22.5425
6 C1x C 25.4167 -21.9824
7 C1z C 24.0864 -21.4923
8 C1a C 26.3270 -25.4832
9 C8x C 21.8459 -24.6430
10 C8x C 20.6556 -23.9428
11 C8y C 20.6556 -22.5425
12 C8y C 21.8459 -21.8423
13 O2a O 19.4654 -21.9124
14 O2x O 22.1960 -20.2320
15 C1y C 23.5963 -20.1620
16 C1x C 24.2265 -19.0417
17 C1y C 25.6268 -19.0417
18 C2x C 26.3270 -20.2320
19 C2x C 25.6268 -21.4923
20 O1a O 26.3270 -17.7814
21 C1a C 18.2792 -22.6565
BOND 24
1 3 4 1
2 1 5 2
3 4 6 1
4 2 3 1
5 5 7 1
6 1 2 1
7 7 6 1 #Down
8 3 8 1
9 1 9 1
10 9 10 2
11 10 11 1
12 11 12 2
13 5 12 1
14 11 13 1
15 12 14 1
16 14 15 1
17 7 15 1
18 15 16 1
19 16 17 1
20 17 18 1
21 7 19 1
22 19 18 2
23 17 20 1 #Up
24 13 21 1
|
|---|
