KEGG   COMPOUND: C01946
Entry
C01946                      Compound                               
Name
Oleandomycin;
Amimycin;
Landomycin;
Matromycin;
Romicil
Formula
C35H61NO12
Exact mass
687.4194
Mol weight
687.8583
Structure
Sequence
0 Mak  1 Mtk  2 Mtn  3 Mte  4 Mtk  5 Mtk  6 Mtn
  Gene
0-2 oleA1 [UP:Q9KIV4]; 3-4 oleA2 [UP:Q9KIV3]; 5-6 oleA3
[UP:Q07017]
  Organism
Streptomyces antibioticus
  Type
PK
Remark
ATC code: J01FA05
Drug group: DG00603
Reaction
R03780 R06457
Pathway
map00522  Biosynthesis of 12-, 14- and 16-membered macrolides
map01052  Type I polyketide structures
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
map02010  ABC transporters
Module
M00775  Oleandomycin biosynthesis, malonyl-CoA + methylmalonyl-CoA => 8,8a-deoxyoleandolide => oleandomycin
Enzyme
2.7.1.136
Brite
Compounds with biological roles [BR:br08001]
 Antibiotics
  Polyketides and nonribosomal peptides
   Macrolides
    C01946  Oleandomycin
Lipids [BR:br08002]
 PK  Polyketides
  PK04 Macrolides and lactone polyketides
   C01946  Oleandomycin
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J01 ANTIBACTERIALS FOR SYSTEMIC USE
   J01F MACROLIDES, LINCOSAMIDES AND STREPTOGRAMINS
    J01FA Macrolides
     J01FA05 Oleandomycin
      C01946  Oleandomycin
Drug groups [BR:br08330]
 Antibacterial
  DG01551  Macrolide antibiotic
   DG01874  14-membered ring macrolide antibiotic
    DG00603  Oleandomycin
     C01946  Oleandomycin
Secondary metabolites in pathway maps [br08011.html]
 Biosynthetic pathways and modules of secondary metabolites
  C01946
Other DBs
CAS: 3922-90-5
PubChem: 5050
ChEBI: 16869
LIPIDMAPS: LMPK04000007
3DMET: B01521
NIKKAJI: J10.660G
KCF data

ATOM        48
            1   C1z C    23.5055  -12.4797
            2   C1x C    23.4937  -11.0541
            3   O2x O    24.7191  -11.7728
            4   C1x C    23.5055  -13.8816
            5   C5x C    22.2921  -11.7728
            6   C1y C    24.7249  -14.5709
            7   C1y C    21.0845  -12.4797
            8   O5x O    22.2921  -10.3826
            9   C1y C    24.7249  -15.9729
            10  C1a C    25.9267  -13.8757
            11  C1y C    21.0845  -13.8816
            12  C1a C    19.8709  -11.7728
            13  C1y C    23.5055  -16.6738
            14  O2a O    25.9207  -16.6738
            15  C1y C    19.8709  -14.5709
            16  O1a O    22.2921  -14.5709
            17  C1y C    23.5055  -18.0700
            18  C1a C    22.6421  -15.6229
            19  C1y C    27.3287  -16.6444
            20  C1y C    19.8709  -15.9729
            21  C1a C    18.6634  -13.8757
            22  O2a O    24.7249  -18.7651
            23  C1y C    22.2921  -18.7651
            24  C1y C    28.0060  -15.4250
            25  O2x O    28.0474  -17.8402
            26  O7x O    21.0845  -16.6738
            27  C1a C    18.6575  -16.6798
            28  C1y C    25.9325  -19.4602
            29  C7x C    21.0845  -18.0700
            30  C1a C    22.2921  -20.1611
            31  C1y C    29.4022  -15.4014
            32  O1a O    27.2755  -14.2174
            33  C1y C    29.4374  -17.8166
            34  C1x C    25.9325  -20.8680
            35  O2x O    27.1401  -18.7651
            36  O6a O    19.8709  -18.7651
            37  C1x C    30.1149  -16.5973
            38  N1c N    30.0796  -14.1820
            39  C1a C    30.8394  -18.2584
            40  C1y C    27.1401  -21.5573
            41  C1y C    28.3477  -19.4602
            42  C1a C    29.3491  -12.9862
            43  C1a C    31.4698  -14.2285
            44  C1y C    28.3477  -20.8680
            45  O2a O    27.1461  -22.9534
            46  C1a C    29.5553  -18.7651
            47  O1a O    29.5553  -21.5573
            48  C1a C    25.9385  -23.6543
BOND        51
            1     1   2 1
            2     1   3 1 #Up
            3     1   4 1
            4     1   5 1
            5     4   6 1
            6     5   7 1
            7     5   8 2
            8     6   9 1
            9     6  10 1 #Down
            10    7  11 1
            11    7  12 1 #Up
            12    9  13 1
            13    9  14 1 #Down
            14   11  15 1
            15   11  16 1 #Up
            16   13  17 1
            17   13  18 1 #Down
            18   19  14 1 #Up
            19   15  20 1
            20   15  21 1 #Down
            21   17  22 1 #Down
            22   17  23 1
            23   19  24 1
            24   19  25 1
            25   20  26 1
            26   20  27 1 #Down
            27   28  22 1 #Down
            28   23  29 1
            29   23  30 1 #Up
            30   24  31 1
            31   24  32 1 #Down
            32   25  33 1
            33   28  34 1
            34   28  35 1
            35   29  36 2
            36   31  37 1
            37   31  38 1 #Up
            38   33  39 1 #Up
            39   34  40 1
            40   35  41 1
            41   38  42 1
            42   38  43 1
            43   40  44 1
            44   40  45 1 #Up
            45   41  46 1 #Up
            46   44  47 1 #Down
            47   45  48 1
            48    2   3 1
            49   26  29 1
            50   33  37 1
            51   41  44 1

» Japanese version

  All links  
Ontology (1)   
   KEGG BRITE (1)   
Pathway (6)   
   KEGG PATHWAY (5)   
   KEGG MODULE (1)   
Chemical substance (14)   
   PubChem (1)   
   ChEBI (1)   
   3DMET (1)   
   HSDB (1)   
   LIPIDMAPS (1)   
   MASSBANK (8)   
   NIKKAJI (1)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG REACTION (2)   
Gene (1)   
   KEGG GENES (1)   
All databases (25)   

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