| | COMPOUND: C06868 | |
Entry |
|
Name |
|
Formula |
C15H12N2O
|
Exact mass |
236.095
|
Mol weight |
236.2686
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Structure |
|
Remark |
|
Reaction |
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Pathway |
map00982 | Drug metabolism - cytochrome P450 |
|
Enzyme |
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Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
N NERVOUS SYSTEM
N03 ANTIEPILEPTICS
N03A ANTIEPILEPTICS
N03AF Carboxamide derivatives
N03AF01 Carbamazepine
D00252 Carbamazepine (JP18/USP/INN) <JP/US>
USP drug classification [BR:br08302]
Anticonvulsants
Sodium Channel Agents
Carbamazepine
D00252 Carbamazepine (JP18/USP/INN)
Bipolar Agents
Mood Stabilizers
Carbamazepine
D00252 Carbamazepine (JP18/USP/INN)
Central Nervous System Agents
Central Nervous System, Other
Carbamazepine
D00252 Carbamazepine (JP18/USP/INN)
Therapeutic category of drugs in Japan [BR:br08301]
1 Agents affecting nervous system and sensory organs
11 Agents affecting central nervous system
113 Antiepileptics
1139 Others
D00252 Carbamazepine (JP18/USP/INN)
117 Psychotropics
1179 Others
D00252 Carbamazepine (JP18/USP/INN)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG03199 Antiepileptic agent
DG02034 Carboxamide antiepileptic
D00252 Carbamazepine
Metabolizing enzyme substrate
DG01633 CYP3A/CYP3A4 substrate
DG02913 CYP3A4 substrate
D00252 Carbamazepine
Metabolizing enzyme inducer
DG02853 CYP3A/CYP3A4 inducer
DG01635 CYP3A4 inducer
D00252 Carbamazepine
Transporter inducer
DG01893 ABCB1 inducer
D00252 Carbamazepine
Drug classes [BR:br08332]
Neuropsychiatric agent
DG03199 Antiepileptic agent
D00252 Carbamazepine
Target-based classification of drugs [BR:br08310]
Ion channels
Voltage-gated ion channels
Sodium channels
SCN1A
D00252 Carbamazepine (JP18/USP/INN) <JP/US>
SCN2A
D00252 Carbamazepine (JP18/USP/INN) <JP/US>
SCN3A
D00252 Carbamazepine (JP18/USP/INN) <JP/US>
SCN4A
D00252 Carbamazepine (JP18/USP/INN) <JP/US>
SCN5A
D00252 Carbamazepine (JP18/USP/INN) <JP/US>
SCN8A
D00252 Carbamazepine (JP18/USP/INN) <JP/US>
SCN9A
D00252 Carbamazepine (JP18/USP/INN) <JP/US>
SCN10A
D00252 Carbamazepine (JP18/USP/INN) <JP/US>
SCN11A
D00252 Carbamazepine (JP18/USP/INN) <JP/US>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
Chemicals
D00252 Carbamazepine
Drug metabolizing enzymes and transporters [br08309.html]
Drug metabolizing enzymes
D00252
Drug transporters
D00252
Pharmacogenomic biomarkers [br08341.html]
Polymorphisms and mutations affecting drug response
D00252
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Other DBs |
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KCF data |
ATOM 18
1 C8y C 25.8139 -16.0918
2 N1y N 27.0679 -15.4768
3 C8y C 28.3385 -16.0677
4 C8y C 28.6646 -17.4200
5 C8y C 25.5184 -17.4703
6 C2x C 27.8110 -18.5337
7 C2x C 26.4090 -18.5521
8 C8x C 24.7745 -15.1529
9 C8x C 23.4416 -15.5834
10 C8x C 23.1462 -16.9619
11 C8x C 24.1856 -17.9009
12 C8x C 30.0177 -17.7825
13 C8x C 31.0081 -16.7920
14 C8x C 30.6456 -15.4389
15 C8x C 29.2926 -15.0764
16 C5a C 27.1235 -14.0772
17 O5a O 25.8857 -13.3793
18 N1a N 28.3127 -13.3740
BOND 20
1 3 4 1
2 1 5 1
3 4 6 1
4 2 3 1
5 5 7 1
6 1 2 1
7 6 7 2
8 1 8 2
9 8 9 1
10 9 10 2
11 10 11 1
12 5 11 2
13 4 12 2
14 12 13 1
15 13 14 2
16 14 15 1
17 15 3 2
18 2 16 1
19 16 17 2
20 16 18 1
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