KEGG   Homo sapiens (human): 4025
Entry
4025              CDS       T01001                                 
Symbol
LPO, SPO
Name
(RefSeq) lactoperoxidase
  KO
K12550  lactoperoxidase [EC:1.11.1.7]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04970  Salivary secretion
hsa05208  Chemical carcinogenesis - reactive oxygen species
Network
nt06251  CYP-mediated ROS formation (cancer)
  Element
N01404  17beta-estradiol to CYP-mediated metabolism
N01405  17beta-estradiol to CYP-mediated metabolism
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09150 Organismal Systems
  09154 Digestive system
   04970 Salivary secretion
    4025 (LPO)
 09160 Human Diseases
  09161 Cancer: overview
   05208 Chemical carcinogenesis - reactive oxygen species
    4025 (LPO)
Enzymes [BR:hsa01000]
 1. Oxidoreductases
  1.11  Acting on a peroxide as acceptor
   1.11.1  Peroxidases
    1.11.1.7  peroxidase
     4025 (LPO)
SSDB
Motif
Pfam: An_peroxidase
Other DBs
NCBI-GeneID: 4025
NCBI-ProteinID: NP_006142
OMIM: 150205
HGNC: 6678
Ensembl: ENSG00000167419
UniProt: P22079
Position
17:58238584..58268518
AA seq 712 aa
MRVLLHLPALLASLILLQAAASTTRAQTTRTSAISDTVSQAKVQVNKAFLDSRTRLKTAM
SSETPTSRQLSEYLKHAKGRTRTAIRNGQVWEESLKRLRQKASLTNVTDPSLDLTSLSLE
VGCGAPAPVVRCDPCSPYRTITGDCNNRRKPALGAANRALARWLPAEYEDGLSLPFGWTP
GKTRNGFPLPLAREVSNKIVGYLNEEGVLDQNRSLLFMQWGQIVDHDLDFAPDTELGSSE
YSKAQCDEYCIQGDNCFPIMFPPNDPKAGTQGKCMPFFRAGFVCPTPPYKSLAREQINAL
TSFLDASFVYSSEPSLASRLRNLSSPLGLMAVNQEVSDHGLPYLPYDSKKPSPCEFINTT
ARVPCFLAGDSRASEHILLATSHTLFLREHNRLARELKRLNPQWDGEKLYQEARKILGAF
VQIITFRDYLPILLGDHMQKWIPPYQGYSESVDPRISNVFTFAFRFGHLEVPSSMFRLDE
NYQPWGPEPELPLHTLFFNTWRMVKDGGIDPLVRGLLAKKSKLMKQNKMMTGELRNKLFQ
PTHRIHGFDLAAINTQRCRDHGQPGYNSWRAFCDLSQPQTLEELNTVLKSKMLAKKLLGL
YGTPDNIDIWIGAIAEPLVERGRVGPLLACLLGKQFQQIRDGDRFWWENPGVFTNEQKDS
LQKMSFSRLVCDNTRITKVPRDPFWANSYPYDFVDCSAIDKLDLSPWASVKN
NT seq 2139 nt   +upstreamnt  +downstreamnt
atgagggtccttctccatctcccagccctcctggcttccctcatcttgcttcaggctgca
gcatctaccacaagagcgcagactaccagaacctctgccatctccgatactgtgagtcag
gccaaggtccaagtcaacaaggccttcctggactcccgaaccaggctgaagaccgccatg
agctctgagactcccaccagccgacagctctcagaatacctcaagcatgccaaaggccgg
acgcgcacagccatccgcaatggacaggtgtgggaggagtctttaaagagactgaggcag
aaggcatccttgaccaatgtcacagatcccagcctggacttgacttcactgtctctggag
gtgggctgtggtgctcctgctcccgtggtgagatgcgacccgtgcagcccttaccgcacc
attacgggagactgcaataacaggaggaagcctgcgctgggcgccgccaacagggctctg
gcgcgctggctgcccgcggagtacgaggacgggctctccctgcccttcggctggacgccg
gggaagacgcgcaacggcttccctctcccgctggcccgggaggtatctaacaagattgtt
ggctatctgaatgaggagggtgttctggaccaaaacaggtccctgctcttcatgcagtgg
ggtcagattgtggatcatgacctggactttgcccctgacaccgagctggggagtagcgag
tactccaaagcccagtgtgatgagtactgtatccagggagacaactgcttccccatcatg
ttcccacccaatgaccccaaggcggggactcaagggaaatgcatgcctttcttccgagct
gggttcgtctgccccactccaccctacaagtccctggcccgagagcagatcaacgctctg
acctccttcctggatgccagctttgtgtacagctccgagccaagcctggccagccgcctc
cgcaacctcagcagccccctgggcctcatggctgtcaaccaggaggtctcagaccatgga
ctaccctacctgccctatgacagcaagaagccaagcccctgtgagttcatcaacaccact
gcccgtgtgccctgcttcctggcaggagattctcgagcctcagagcatattctgctggcc
acatcccacaccctctttctccgcgagcataaccggctggccagagaactaaagagactc
aaccctcagtgggatggagagaagctctaccaggaagcccggaaaatcctgggagccttc
gtgcagattatcacctttagggactacctacccattttgctaggtgaccacatgcagaag
tggatacccccatatcaaggctacagtgaatctgtggatcccagaatttccaatgtcttc
accttcgccttccgctttggccacttggaggtcccctctagtatgttccgcctggatgag
aattatcagccatgggggccagaaccagaactccccctccacaccctcttcttcaacact
tggaggatggtcaaagatggtggaattgatcctctggtgcggggcctgctggccaagaaa
tccaagctgatgaaacagaataaaatgatgactggagagctgcgcaacaagcttttccag
ccaactcacaggatccatggctttgacctggctgccatcaacacacagcgttgccgggac
catgggcaacctgggtacaattcctggagagccttctgtgacctctcacagccgcagaca
ctagaggagttgaacacagtgctgaagagcaagatgctggccaagaagttactgggtctc
tacgggacccctgacaacatcgacatctggataggggccattgctgagccgctggtggaa
aggggtcgggtggggcctctcctggcctgcctcttgggcaagcagttccagcagatccgt
gatggagacaggttctggtgggaaaaccctggggtcttcacgaacgagcagaaggactct
ctacagaaaatgtccttctcacgccttgtctgtgacaacacccgcatcaccaaggtccca
cgggacccattctgggccaacagctacccctatgacttcgtggattgctcagccatcgac
aagctggacctgtcaccctgggcctcagtgaagaattag

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (2)   
   KEGG PATHWAY (2)   
Network (3)   
   KEGG NETWORK (3)   
Disease (1)   
   OMIM (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (14)   
   KEGG ORTHOLOGY (1)   
   RefGene (8)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (9)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (7)   
DNA sequence (38)   
   RefSeq(nuc) (8)   
   GenBank (15)   
   EMBL (15)   
Protein domain (1)   
   Pfam (1)   
All databases (72)   

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