KEGG   Homo sapiens (human): 11184
Entry
11184             CDS       T01001                                 
Symbol
MAP4K1, HPK1
Name
(RefSeq) mitogen-activated protein kinase kinase kinase kinase 1
  KO
K04408  mitogen-activated protein kinase kinase kinase kinase 1 [EC:2.7.11.1]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04010  MAPK signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    11184 (MAP4K1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:hsa01001]
    11184 (MAP4K1)
Enzymes [BR:hsa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     11184 (MAP4K1)
Protein kinases [BR:hsa01001]
 Serine/threonine kinases: STE group
  STE20 family
   11184 (MAP4K1)
SSDB
Motif
Pfam: Pkinase CNH PK_Tyr_Ser-Thr ABC1 Pkinase_fungal
Other DBs
NCBI-GeneID: 11184
NCBI-ProteinID: NP_009112
OMIM: 601983
HGNC: 6863
Ensembl: ENSG00000104814
UniProt: Q92918
Structure
Position
19:complement(38587641..38617953)
AA seq 833 aa
MDVVDPDIFNRDPRDHYDLLQRLGGGTYGEVFKARDKVSGDLVALKMVKMEPDDDVSTLQ
KEILILKTCRHANIVAYHGSYLWLQKLWICMEFCGAGSLQDIYQVTGSLSELQISYVCRE
VLQGLAYLHSQKKIHRDIKGANILINDAGEVRLADFGISAQIGATLARRLSFIGTPYWMA
PEVAAVALKGGYNELCDIWSLGITAIELAELQPPLFDVHPLRVLFLMTKSGYQPPRLKEK
GKWSAAFHNFIKVTLTKSPKKRPSATKMLSHQLVSQPGLNRGLILDLLDKLKNPGKGPSI
GDIEDEEPELPPAIPRRIRSTHRSSSLGIPDADCCRRHMEFRKLRGMETRPPANTARLQP
PRDLRSSSPRKQLSESSDDDYDDVDIPTPAEDTPPPLPPKPKFRSPSDEGPGSMGDDGQL
SPGVLVRCASGPPPNSPRPGPPPSTSSPHLTAHSEPSLWNPPSRELDKPPLLPPKKEKMK
RKGCALLVKLFNGCPLRIHSTAAWTHPSTKDQHLLLGAEEGIFILNRNDQEATLEMLFPS
RTTWVYSINNVLMSLSGKTPHLYSHSILGLLERKETRAGNPIAHISPHRLLARKNMVSTK
IQDTKGCRACCVAEGASSGGPFLCGALETSVVLLQWYQPMNKFLLVRQVLFPLPTPLSVF
ALLTGPGSELPAVCIGVSPGRPGKSVLFHTVRFGALSCWLGEMSTEHRGPVQVTQVEEDM
VMVLMDGSVKLVTPEGSPVRGLRTPEIPMTEAVEAVAMVGGQLQAFWKHGVQVWALGSDQ
LLQELRDPTLTFRLLGSPRLECSGTISPHCNLLLPGSSNSPASASRVAGITGL
NT seq 2502 nt   +upstreamnt  +downstreamnt
atggacgtcgtggaccctgacattttcaatagagacccccgggaccactatgacctgcta
cagcggctgggtggcggcacgtatggggaagtctttaaggctcgagacaaggtgtcaggg
gacctggtggcactgaagatggtgaagatggagcctgatgatgatgtctccacccttcag
aaggaaatcctcatattgaaaacttgccggcacgccaacatcgtggcctaccatgggagt
tatctctggttgcagaaactctggatctgcatggaattctgtggggctggttctctccag
gacatctaccaagtgacaggctccctgtcagagctccagattagctatgtctgccgggaa
gtgctccagggactggcctatttgcactcacagaagaagatacacagggacatcaaggga
gctaacatcctcatcaatgatgctggggaggtcagattggctgactttggcatctcggcc
cagattggggctacactggccagacgcctctctttcattgggacaccctactggatggct
ccggaagtggcagctgtggccctgaagggaggatacaatgagctgtgtgacatctggtcc
ctgggcatcacggccatcgaactggccgagctacagccaccgctctttgatgtgcaccct
ctcagagttctcttcctcatgaccaagagtggctaccagcctccccgactgaaggaaaaa
ggcaaatggtcggctgccttccacaacttcatcaaagtcactctgactaagagtcccaag
aaacgacccagcgccaccaagatgctcagtcatcaactggtatcccagcctgggctgaat
cgaggcctgatcctggatcttcttgacaaactgaagaatcccgggaaaggaccctccatt
ggggacattgaggatgaggagcccgagctaccccctgctatccctcggcggatcagatcc
acccaccgctccagctctctggggatcccagatgcagactgctgtcggcggcacatggag
ttcaggaagctccgaggaatggagaccagacccccagccaacaccgctcgcctacagcct
cctcgagacctcaggagcagcagccccaggaagcaactgtcagagtcgtctgacgatgac
tatgacgacgtggacatccccacccctgcagaggacacacctcctccacttccccccaag
cccaagttccgttctccatcagacgagggtcctgggagcatgggggatgatgggcagctg
agcccgggggtgctggtccggtgtgccagtgggcccccaccaaacagcccccgtcctggg
cctcccccatccaccagcagcccccacctcaccgcccattcagaaccctcactctggaac
ccaccctcccgggagcttgacaagcccccacttctgccccccaagaaggaaaagatgaag
agaaagggatgtgcccttctcgtaaagttgttcaatggctgccccctccggatccacagc
acggccgcctggacacatccctccaccaaggaccagcacctgctcctgggggcagaggaa
ggcatcttcatcctgaaccggaatgaccaggaggccacgctggaaatgctctttcctagc
cggactacgtgggtgtactccatcaacaacgttctcatgtctctctcaggaaagaccccc
cacctgtattctcatagcatccttggcctgctggaacggaaagagaccagagcaggaaac
cccatcgctcacattagcccccaccgcctactggcaaggaagaacatggtttccaccaag
atccaggacaccaaaggctgccgggcgtgctgtgtggcggagggtgcgagctctgggggc
ccgttcctgtgcggtgcattggagacgtccgttgtcctgcttcagtggtaccagcccatg
aacaaattcctgcttgtccggcaggtgctgttcccactgccgacgcctctgtccgtgttc
gcgctgctgaccgggccaggctctgagctgcccgctgtgtgcatcggcgtgagccccggg
cggccggggaagtcggtgctcttccacacggtgcgctttggcgcgctctcttgctggctg
ggcgagatgagcaccgagcacaggggacccgtgcaggtgacccaggtagaggaagatatg
gtgatggtgttgatggatggctctgtgaagctggtgaccccggaggggtccccagtccgg
ggacttcgcacacctgagatccccatgaccgaagcggtggaggccgtggctatggttgga
ggtcagcttcaggccttctggaagcatggagtgcaggtgtgggctctaggctcggatcag
ctgctacaggagctgagagaccctaccctcactttccgtctgcttggctcccccaggctg
gagtgcagtggcacgatctcgcctcactgcaacctcctcctcccaggttcaagcaattct
cctgcctcagcctcccgagtagctgggattacaggcctgtag

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (1)   
   KEGG PATHWAY (1)   
Disease (1)   
   OMIM (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (24)   
   KEGG ORTHOLOGY (1)   
   RefGene (18)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (8)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (6)   
DNA sequence (18)   
   RefSeq(nuc) (6)   
   GenBank (6)   
   EMBL (6)   
3D Structure (23)   
   PDB (23)   
Protein domain (5)   
   Pfam (5)   
All databases (85)   

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