KEGG   Homo sapiens (human): 53904
Entry
53904             CDS       T01001                                 
Symbol
MYO3A, DFNA90, DFNB30
Name
(RefSeq) myosin IIIA
  KO
K08834  myosin III [EC:2.7.11.1]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04814  Motor proteins
Disease
H00604  Deafness, autosomal dominant
H00605  Deafness, autosomal recessive
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09140 Cellular Processes
  09142 Cell motility
   04814 Motor proteins
    53904 (MYO3A)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:hsa01001]
    53904 (MYO3A)
  09183 Protein families: signaling and cellular processes
   03037 Cilium and associated proteins [BR:hsa03037]
    53904 (MYO3A)
   04812 Cytoskeleton proteins [BR:hsa04812]
    53904 (MYO3A)
Enzymes [BR:hsa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     53904 (MYO3A)
Protein kinases [BR:hsa01001]
 Serine/threonine kinases: STE group
  STE20 family
   53904 (MYO3A)
Cilium and associated proteins [BR:hsa03037]
 Other cilia and associated proteins
  Stereociliary proteins
   53904 (MYO3A)
Cytoskeleton proteins [BR:hsa04812]
 Eukaryotic cytoskeleton proteins
  Actin filaments / Microfilaments
   Actin-binding proteins
    Myosins
     53904 (MYO3A)
SSDB
Motif
Pfam: Myosin_head Pkinase PK_Tyr_Ser-Thr IQ ABC1 Kinase-like AAA_22 nSTAND3
Other DBs
NCBI-GeneID: 53904
NCBI-ProteinID: NP_059129
OMIM: 606808
HGNC: 7601
Ensembl: ENSG00000095777
UniProt: Q8NEV4
Structure
Position
10:25934229..26212532
AA seq 1616 aa
MFPLIGKTIIFDNFPDPSDTWEITETIGKGTYGKVFKVLNKKNGQKAAVKILDPIHDIDE
EIEAEYNILKALSDHPNVVRFYGIYFKKDKVNGDKLWLVLELCSGGSVTDLVKGFLKRGE
RMSEPLIAYILHEALMGLQHLHNNKTIHRDVKGNNILLTTEGGVKLVDFGVSAQLTSTRH
RRNTSVGTPFWMAPEVIACEQQLDTTYDARCDTWSLGITAIELGDGDPPLADLHPMRALF
KIPRNPPPKLRQPELWSAEFNDFISKCLTKDYEKRPTVSELLQHKFITQIEGKDVMLQKQ
LTEFIGIHQCMGGTEKARRERIHTKKGNFNRPLISNLKDVDDLATLEILDENTVSEQLEK
CYSRDQIYVYVGDILIALNPFQSLGLYSTKHSKLYIGSKRTASPPHIFAMADLGYQSMIT
YNSDQCIVISGESGAGKTENAHLLVQQLTVLGKANNRTLQEKILQVNNLVEAFGNACTII
NDNSSRFGKYLEMKFTSSGAVVGAQISEYLLEKSRVIHQAIGEKNFHIFYYIYAGLAEKK
KLAHYKLPENKPPRYLQNDHLRTVQDIMNNSFYKSQYELIEQCFKVIGFTMEQLGSIYSI
LAAILNVGNIEFSSVATEHQIDKSHISNHTALENCASLLCIRADELQEALTSHCVVTRGE
TIIRPNTVEKATDVRDAMAKTLYGRLFSWIVNCINSLLKHDSSPSGNGDELSIGILDIFG
FENFKKNSFEQLCINIANEQIQYYYNQHVFAWEQNEYLNEDVDARVIEYEDNWPLLDMFL
QKPMGLLSLLDEESRFPKATDQTLVEKFEGNLKSQYFWRPKRMELSFGIHHYAGKVLYNA
SGFLAKNRDTLPTDIVLLLRSSDNSVIRQLVNHPLTKTGNLPHSKTKNVINYQMRTSEKL
INLAKGDTGEATRHARETTNMKTQTVASYFRYSLMDLLSKMVVGQPHFVRCIKPNSERQA
RKYDKEKVLLQLRYTGILETARIRRLGFSHRILFANFIKRYYLLCYKSSEEPRMSPDTCA
TILEKAGLDNWALGKTKVFLKYYHVEQLNLMRKEAIDKLILIQACVRAFLCSRRYQKIQE
KRKESAIIIQSAARGHLVRKQRKEIVDMKNTAVTTIQTSDQEFDYKKNFENTRESFVKKQ
AENAISANERFISAPNNKGSVSVVKTSTFKPEEETTNAVESNNRVYQTPKKMNNVYEEEV
KQEFYLVGPEVSPKQKSVKDLEENSNLRKVEKEEAMIQSYYQRYTEERNCEESKAAYLER
KAISERPSYPVPWLAENETSFKKTLEPTLSQRSIYQNANSMEKEKKTSVVTQRAPICSQE
EGRGRLRHETVKERQVEPVTQAQEEEDKAAVFIQSKYRGYKRRQQLRKDKMSSFKHQRIV
TTPTEVARNTHNLYSYPTKHEEINNIKKKDNKDSKATSEREACGLAIFSKQISKLSEEYF
ILQKKLNEMILSQQLKSLYLGVSHHKPINRRVSSQQCLSGVCKGEEPKILRPPRRPRKPK
TLNNPEDSTYYYLLHKSIQEEKRRPRKDSQGKLLDLEDFYYKEFLPSRSGPKEHSPSLRE
RRPQQELQNQCIKANERCWAAESPEKEEEREPAANPYDFRRLLRKTSQRRRLVQQS
NT seq 4851 nt   +upstreamnt  +downstreamnt
atgtttccattaattggaaaaacaatcatctttgataactttcctgatccttctgataca
tgggaaatcactgagacaattggcaaaggaacttatgggaaagtttttaaagtattgaat
aagaaaaatggccaaaaagcagcagtcaaaattcttgatccaattcacgatattgacgaa
gagattgaagcagaatataacatcttaaaagcactttctgaccaccctaatgtggtcaga
ttctatgggatatactttaagaaggataaagtaaatggagacaagctgtggttggttctt
gagctctgcagtggaggatcagtgactgaccttgtgaaaggatttctgaagaggggtgaa
agaatgagtgagcctctaattgcctatattttacatgaagcactaatgggacttcaacat
ttgcataacaacaaaactatccacagagatgtgaaaggcaataacattctattgaccacg
gaaggtggagtgaaactagtagattttggtgtgtctgcacagctcaccagtacccggcac
cgtcggaacacatccgtaggaacaccgttttggatggctcctgaggtgattgcatgtgaa
cagcaattggataccacttatgacgccagatgtgacacttggtccctgggtatcacggcc
attgagctgggtgatggagatcctccactagctgaccttcatcccatgagagcactcttc
aaaataccaaggaatccacccccaaaactaaggcagcctgagctatggtcagcagaattc
aatgacttcataagcaagtgcttgactaaagattatgaaaagcgtccaacagtgtcagaa
cttttacagcataaattcattactcaaattgagggcaaagatgtgatgctacaaaaacaa
ctaacggaattcattggcatccatcaatgcatgggaggcacagaaaaggccagacgtgaa
cgtattcacacgaagaaagggaacttcaaccgacctctaatatccaatctgaaggatgta
gatgatttagcaaccctagaaattttggatgagaatacagtctcagagcaacttgagaag
tgttattccagagatcagatctacgtctatgtgggagacatactcattgctcttaaccct
tttcagagtctgggtctttactccacaaagcattccaaactatatattggatcaaagaga
actgccagtcctcctcacatttttgcaatggctgacttaggatatcaatctatgataaca
tataattcagatcagtgcattgttatttctggagaaagtggtgctggaaagactgaaaat
gctcatcttttagttcagcagctgacagtgcttggaaaggctaataacagaaccttgcaa
gagaagattttacaagtgaacaatttggtagaagcctttggcaatgcctgcactattata
aatgacaattctagcagatttggaaaatacttagaaatgaaattcacctcttctggagcg
gtagtgggagcacagatttctgaatatctcctggaaaaatcccgagttatccaccaagct
attggagaaaaaaattttcatattttttactacatttatgctggtttggctgaaaagaag
aaactagcccattacaaactgcctgaaaataagcctcccaggtacctacaaaatgaccac
ctcagaacagtacaagacatcatgaataatagtttctataaatcccagtatgaattaatt
gagcaatgtttcaaagtcataggttttacaatggagcaacttggtagtatatacagcata
ctcgctgcaatcttgaatgttggcaacattgaattttcttctgtggcaactgaacaccag
attgacaagagccacatttctaatcatacagccctggagaactgtgcttctttgctttgc
attcgggcagatgagctacaagaagctctcacctcccactgtgtggtcactagaggagaa
acaattatacgacccaatactgtagaaaaagctaccgatgtcagggatgccatggctaaa
actttatatggacgtctctttagttggatagtcaattgcattaacagtttgttgaagcat
gactcatcaccaagtgggaatggtgatgagctgagcattggcattcttgatatatttggc
tttgaaaatttcaaaaaaaattccttcgagcagctgtgcattaacattgcaaatgaacaa
attcagtattattataatcaacatgtgtttgcatgggaacagaatgaatacctaaatgaa
gatgtggatgctagagttattgaatatgaggataactggcccctcttagatatgtttctg
caaaagccaatgggtttactttccctacttgatgaagaaagtagatttcccaaggccact
gaccagactcttgtagaaaaatttgaaggtaacctgaaatcacaatacttctggagaccc
aaaagaatggaacttagttttggaattcaccattatgcaggaaaggtcctctataatgca
agtggattcttagccaaaaacagagacactcttcctactgacattgtgctacttttgagg
tcatccgacaacagtgtaattaggcaactagtcaaccaccctctgaccaaaacaggtaat
ctgccacattctaaaactaaaaatgttataaactatcaaatgaggacttcagaaaaatta
atcaacctggcaaagggcgacactggagaagccacacgtcatgccagagagacaaccaac
atgaaaacacaaacggttgcatcatattttagatattccctgatggatttgttgtctaaa
atggtggtgggccaacctcattttgtccgttgcatcaaaccaaatagtgagcgtcaggca
agaaaatatgacaaagagaaagttctgctacagcttcggtacacaggaattctggaaaca
gcaagaattcgaagactaggattctcccatcggatactttttgctaactttataaagcgg
tactaccttctctgctacaagtcgagcgaggagccccgcatgagccctgacacctgtgcc
accattttggaaaaagctggtctcgataactgggctcttggaaaaacaaaagtgttcctt
aagtattatcacgtggagcagttaaatctaatgcgaaaggaagctattgacaagcttatt
ttgattcaagcttgtgtcagagcattcttgtgttcaagaagataccaaaaaatacaggag
aaaaggaaagaaagcgctataataatacagtcagctgcaagaggacaccttgtcaggaaa
caaagaaaagaaattgttgacatgaaaaacacagcagtaacaaccattcaaacttctgat
caggaattcgactacaagaaaaactttgaaaatacaagggaatctttcgtgaagaaacaa
gcagaaaatgcaatctctgctaatgaaagattcatttcagctccaaataataaaggaagt
gtatctgtagtgaagacttccactttcaaacctgaagaggaaaccaccaatgctgtggag
agtaacaacagagtgtatcagactccaaaaaaaatgaataatgtgtatgaggaagaggtt
aagcaagaattctaccttgtagggccagaagtaagccccaaacagaagtctgtcaaagac
ctggaagagaacagcaatctaaggaaagtggagaaagaggaagctatgatccagagttac
tatcagaggtacacagaggagaggaattgtgaagagtcaaaagcagcatatctagaaagg
aaggccatatcagaaaggccaagctacccagtgccttggttagctgaaaatgagacttcc
tttaaaaaaactttggaacctacacttagccaaaggtcaatttatcaaaatgcaaacagc
atggaaaaagaaaagaagacatctgtagttacccagcgtgcaccgatatgcagccaggag
gaaggcagaggccgtctgaggcatgagacagtcaaagagaggcaagttgaaccagtgaca
caggcccaggaggaagaagataaagcagcggtattcattcagagcaaataccggggttac
aagagaaggcagcagttgaggaaggacaagatgtcttcttttaagcatcagaggattgtc
acaacaccaacagaagtagcaagaaacactcataatttgtattcctatcccacaaaacat
gaggaaatcaataacatcaagaagaaggataacaaagactcgaaagcaacttcagaaaga
gaagcatgtggtttggcaattttttcaaaacagatatcaaagttatctgaagaatatttc
attctgcagaaaaaattgaatgaaatgattttgtcacagcaactgaagtcactttatctg
ggtgtctcgcaccataagccaattaatagacgagtttcttctcagcagtgcctctcaggt
gtctgtaaaggagaggagccaaaaatattgagacccccaagacgaccccggaaacccaaa
acattaaataaccctgaagactccacatactattatctacttcataagtcaatccaagaa
gaaaaacgaagaccaaggaaagacagtcagggaaaattattagatttggaagatttctat
tataaggaatttttgcccagtcgttctggaccaaaggaacatagccctagtttaagagaa
cgaagaccacagcaagaactccagaatcaatgtattaaggctaatgaaaggtgctgggcg
gcggagagccccgagaaggaggaggagagagagccagcagccaacccctacgacttcagg
aggctcctgcgcaaaacctcccagcgccggcgcctcgtccagcagtcctaa

  All links  
Ontology (5)   
   KEGG BRITE (5)   
Pathway (1)   
   KEGG PATHWAY (1)   
Disease (5)   
   KEGG DISEASE (2)   
   OMIM (3)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (22)   
   KEGG ORTHOLOGY (1)   
   RefGene (16)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (44)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (42)   
DNA sequence (68)   
   RefSeq(nuc) (44)   
   GenBank (12)   
   EMBL (12)   
3D Structure (1)   
   PDB (1)   
Protein domain (8)   
   Pfam (8)   
All databases (156)   

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