KEGG   Homo sapiens (human): 5218
Entry
5218              CDS       T01001                                 
Symbol
CDK14, PFTAIRE1, PFTK1
Name
(RefSeq) cyclin dependent kinase 14
  KO
K08821  cyclin-dependent kinase 14 [EC:2.7.11.22]
Organism
hsa  Homo sapiens (human)
Pathway
hsa05202  Transcriptional misregulation in cancer
Network
nt06240  Transcription (cancer)
  Element
N00119  MLL-AF4 fusion to transcriptional activation
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09160 Human Diseases
  09161 Cancer: overview
   05202 Transcriptional misregulation in cancer
    5218 (CDK14)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:hsa01001]
    5218 (CDK14)
Enzymes [BR:hsa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.22  cyclin-dependent kinase
     5218 (CDK14)
Protein kinases [BR:hsa01001]
 Serine/threonine kinases: CMGC group
  CDK family
   5218 (CDK14)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr ABC1 Haspin_kinase Kinase-like TruB_C_2
Other DBs
NCBI-GeneID: 5218
NCBI-ProteinID: NP_001274064
OMIM: 610679
HGNC: 8883
Ensembl: ENSG00000058091
UniProt: O94921
Position
7:90596321..91210590
AA seq 469 aa
MCDLIEPQPAEKIGKMKKLRRTLSESFSRIALKKDDTTFDEICVTKMSTRNCQGMDSVIK
PLDTIPEDKKVRVQRTQSTFDPFEKPANQVKRVHSENNACINFKTSSTGKESPKVRRHSS
PSSPTSPKFGKADSYEKLEKLGEGSYATVYKGKSKVNGKLVALKVIRLQEEEGTPFTAIR
EASLLKGLKHANIVLLHDIIHTKETLTLVFEYVHTDLCQYMDKHPGGLHPDNVKLFLFQL
LRGLSYIHQRYILHRDLKPQNLLISDTGELKLADFGLARAKSVPSHTYSNEVVTLWYRPP
DVLLGSTEYSTCLDMWGVGCIFVEMIQGVAAFPGMKDIQDQLERIFLVLGTPNEDTWPGV
HSLPHFKPERFTLYSSKNLRQAWNKLSYVNHAEDLASKLLQCSPKNRLSAQAALSHEYFS
DLPPRLWELTDMSSIFTVPNVRLQPEAGESMRAFGKNNSYGKSLSNSKH
NT seq 1410 nt   +upstreamnt  +downstreamnt
atgtgtgacctcattgagccgcagccggccgagaagatcggcaagatgaagaagttgcgg
agaactttgtcggagagtttcagtcgcattgctttgaagaaagatgacaccacctttgat
gagatatgtgtcacaaagatgtctacacggaactgccagggaatggactcagtgatcaaa
cccctggacacaattcctgaggataaaaaagtcagagttcagaggacacagagcactttt
gacccatttgagaaaccagctaatcaagtaaagagggtgcattctgagaacaatgcttgc
attaactttaagacctcctccactggcaaagagtcacctaaagttaggcggcactccagc
cccagctcgccaacaagtcccaaatttggaaaagctgactcatatgaaaagctggaaaaa
ctaggggaaggatcttatgctacagtatacaaagggaaaagcaaggtaaatgggaagttg
gtagctctgaaggtgatcaggctgcaggaagaagaagggacacctttcacagctatcagg
gaagcttctcttttaaaaggactaaaacatgctaacatagtgctacttcatgacatcatc
cataccaaggagacgctgacacttgtgtttgaatatgtgcacactgatttatgtcagtac
atggacaagcaccctggggggctgcatccagataatgtgaagttgtttttatttcagttg
ctgcgaggtctgtcttacatccaccagcgttatattttgcacagagacctgaaaccacag
aaccttctgatcagtgacacgggggagttaaagctggcagatttcggtcttgcaagagca
aaatccgtccctagccacacatactccaacgaagtggttaccttgtggtacagacctcca
gatgtccttctaggctcaacagaatattccacctgccttgacatgtggggagtaggttgc
atctttgttgaaatgatccaaggagttgctgcttttccaggaatgaaagacattcaggat
caacttgaacgaatatttctggttcttggaacaccaaatgaggacacatggcctggagtt
cattctttaccacattttaagccagaacgctttaccctgtacagctctaaaaaccttaga
caagcatggaataagctcagctatgtgaaccatgcagaggacctggcctccaagctccta
caatgttccccaaagaacagactgtcggcacaggctgccttgagccacgagtattttagt
gacctgccgccacggctatgggaactcaccgacatgtcttctatttttactgtcccaaat
gtgagattgcaaccagaagctggagaaagcatgcgggcctttgggaaaaacaatagttat
ggcaaaagtctatcaaacagcaagcactga

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (1)   
   KEGG PATHWAY (1)   
Network (2)   
   KEGG NETWORK (2)   
Disease (1)   
   OMIM (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (7)   
   KEGG ORTHOLOGY (1)   
   RefGene (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (6)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (4)   
DNA sequence (58)   
   RefSeq(nuc) (4)   
   GenBank (27)   
   EMBL (27)   
Protein domain (6)   
   Pfam (6)   
All databases (86)   

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