KEGG   Homo sapiens (human): 9088
Entry
9088              CDS       T01001                                 
Symbol
PKMYT1, MYT1, PPP1R126
Name
(RefSeq) protein kinase, membrane associated tyrosine/threonine 1
  KO
K06633  membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase [EC:2.7.11.1]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04110  Cell cycle
hsa04114  Oocyte meiosis
hsa04914  Progesterone-mediated oocyte maturation
Drug target
Lunresertib: D12736
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09140 Cellular Processes
  09143 Cell growth and death
   04110 Cell cycle
    9088 (PKMYT1)
   04114 Oocyte meiosis
    9088 (PKMYT1)
 09150 Organismal Systems
  09152 Endocrine system
   04914 Progesterone-mediated oocyte maturation
    9088 (PKMYT1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:hsa01001]
    9088 (PKMYT1)
   01009 Protein phosphatases and associated proteins [BR:hsa01009]
    9088 (PKMYT1)
Enzymes [BR:hsa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     9088 (PKMYT1)
Protein kinases [BR:hsa01001]
 Serine/threonine kinases: Other
  WEE family
   9088 (PKMYT1)
Protein phosphatases and associated proteins [BR:hsa01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    PP1-interacting proteins (PIPs)
     9088 (PKMYT1)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kinase-like ABC1
Other DBs
NCBI-GeneID: 9088
NCBI-ProteinID: NP_004194
OMIM: 602474
HGNC: 29650
Ensembl: ENSG00000127564
UniProt: Q99640 Q0IJ49
Structure
Position
16:complement(2972808..2980446)
AA seq 499 aa
MLERPPALAMPMPTEGTPPPLSGTPIPVPAYFRHAEPGFSLKRPRGLSRSLPPPPPAKGS
IPISRLFPPRTPGWHQLQPRRVSFRGEASETLQSPGYDPSRPESFFQQSFQRLSRLGHGS
YGEVFKVRSKEDGRLYAVKRSMSPFRGPKDRARKLAEVGSHEKVGQHPCCVRLEQAWEEG
GILYLQTELCGPSLQQHCEAWGASLPEAQVWGYLRDTLLALAHLHSQGLVHLDVKPANIF
LGPRGRCKLGDFGLLVELGTAGAGEVQEGDPRYMAPELLQGSYGTAADVFSLGLTILEVA
CNMELPHGGEGWQQLRQGYLPPEFTAGLSSELRSVLVMMLEPDPKLRATAEALLALPVLR
QPRAWGVLWCMAAEALSRGWALWQALLALLCWLWHGLAHPASWLQPLGPPATPPGSPPCS
LLLDSSLSSNWDDDSLGPSLSPEAVLARTVGSTSTPRSRCTPRDALDLSDINSEPPRGSF
PSFEPRNLLSLFEDTLDPT
NT seq 1500 nt   +upstreamnt  +downstreamnt
atgctagaacggcctcctgcactggccatgcccatgcccacggagggcaccccgccacct
ctgagtggcacccccatcccagtcccagcctacttccgccacgcagaacctggattctcc
ctcaagaggcccagggggctcagccggagcctcccacctccgccccctgccaagggcagc
attcccatcagccgcctcttccctcctcggaccccaggctggcaccagctgcagccccgg
cgggtgtcattccggggcgaggcctcagagactctgcagagccctgggtatgacccaagc
cggccagagtccttcttccagcagagcttccagaggctcagccgcctgggccatggctcc
tacggagaggtcttcaaggtgcgctccaaggaggacggccggctctatgcggtaaagcgt
tccatgtcaccattccggggccccaaggaccgggcccgcaagttggccgaggtgggcagc
cacgagaaggtggggcagcacccatgctgcgtgcggctggagcaggcctgggaggagggc
ggcatcctgtacctgcagacggagctgtgcgggcccagcctgcagcaacactgtgaggcc
tggggtgccagcctgcctgaggcccaggtctggggctacctgcgggacacgctgcttgcc
ctggcccatctgcacagccagggcctggtgcaccttgatgtcaagcctgccaacatcttc
ctggggccccggggccgctgcaagctgggtgacttcggactgctggtggagctgggtaca
gcaggagctggtgaggtccaggagggagacccccgctacatggcccccgagctgctgcag
ggctcctatgggacagcagcggatgtgttcagtctgggcctcaccatcctggaagtggca
tgcaacatggagctgccccacggtggggagggctggcagcagctgcgccagggctacctg
ccccctgagttcactgccggtctgtcttccgagctgcgttctgtccttgtcatgatgctg
gagccagaccccaagctgcgggccacggccgaggccctgctggcactgcctgtgttgagg
cagccgcgggcctggggtgtgctgtggtgcatggcagcggaggccctgagccgagggtgg
gccctgtggcaggccctgcttgccctgctctgctggctctggcatgggctggctcaccct
gccagctggctacagcccctgggcccgccagccaccccgcctggctcaccaccctgcagt
ttgctcctggacagcagcctctccagcaactgggatgacgacagcctagggccttcactc
tcccctgaggctgtcctggcccggactgtggggagcacctccaccccccggagcaggtgc
acacccagggatgccctggacctaagtgacatcaactcagagcctcctcggggctccttc
ccctcctttgagcctcggaacctcctcagcctgtttgaggacaccctagacccaacctga

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Ontology (4)   
   KEGG BRITE (4)   
Pathway (3)   
   KEGG PATHWAY (3)   
Disease (1)   
   OMIM (1)   
Drug (1)   
   KEGG DRUG (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (27)   
   KEGG ORTHOLOGY (1)   
   RefGene (18)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (3)   
   OC (1)   
Protein sequence (27)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (24)   
DNA sequence (54)   
   RefSeq(nuc) (24)   
   GenBank (15)   
   EMBL (15)   
3D Structure (14)   
   PDB (14)   
Protein domain (4)   
   Pfam (4)   
All databases (137)   

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