2CNE: Structural Insights into the Design of Nonpeptidic Isothiazolidinone- Containing Inhibitors of Protein Tyrosine Phosphatase 1B

PDB ID: 2CNEDownload
MMDB ID: 41379
PDB Deposition Date: 2006/5/21
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 1.8  Å
Source Organism:
Similar Structures:
Biological Unit for 2CNE: monomeric; determined by author and by software (PQS)
Molecular Components in 2CNE
Label Count Molecule
Protein (1 molecule)
1
Tyrosine-protein Phosphatase Non-receptor Type 1
(Gene symbol: PTPN1)
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
1
N-({4-[DIFLUORO(PHOSPHONO)METHYL]PHENYL}ACETYL)-L-PHENYLALANYL-4-[DIFLUORO(PHOSPHONO)METHYL]-L-PHENYLALANINAMIDEN-({4-[DIFLUORO(PHOSPHONO)METHYL]PHENYL}ACETYL)-L-PHENYLALANYL-4-[DIFLUORO(PHOSPHONO)METHYL]-L-PHENYLALANINAMIDE
2
2
SULFATE IONSULFATE ION
3
1
octyl beta-D-glucopyranosideoctyl beta-D-glucopyranoside
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303