2AYW: Crystal Structure of the complex formed between trypsin and a designed synthetic highly potent inhibitor in the presence of benzamidine at 0.97 A resolution

PDB ID: 2AYWDownload
MMDB ID: 37100
PDB Deposition Date: 2005/9/9
Updated in MMDB: 2012/12
Experimental Method:
x-ray diffraction
Resolution: 0.97  Å
Source Organism:
Similar Structures:
Biological Unit for 2AYW: monomeric; determined by author
Molecular Components in 2AYW
Label Count Molecule
Protein (1 molecule)
1
Cationic Trypsin
(Gene symbol: PRSS1)
Molecule annotation
Chemicals and Non-standard biopolymers (6 molecules)
1
1
CALCIUM IONCALCIUM ION
2
2
2-[2-({[4-(DIAMINOMETHYL)PHENYL]AMINO}CARBONYL)-6-METHOXYPYRIDIN-3-YL]-5-{[(1-FORMYL-2,2-DIMETHYLPROPYL)AMINO]CARBONYL}BENZOIC ACID2-[2-({[4-(DIAMINOMETHYL)PHENYL]AMINO}CARBONYL)-6-METHOXYPYRIDIN-3-YL]-5-{[(1-FORMYL-2,2-DIMETHYLPROPYL)AMINO]CARBONYL}BENZOIC ACID
3
1
BENZAMIDINEBENZAMIDINE
4
1
2-(N-MORPHOLINO)-ETHANESULFONIC ACID2-(N-MORPHOLINO)-ETHANESULFONIC ACID
5
1
GLYCEROLGLYCEROL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303