1K2C: Combining Mutations in HIV-1 Protease to Understand Mechanisms of Resistance

PDB ID: 1K2CDownload
MMDB ID: 103876
PDB Deposition Date: 2001/9/26
Updated in MMDB: 2021/11
Experimental Method:
x-ray diffraction
Resolution: 2.2  Å
Source Organism:
Similar Structures:
Biological Unit for 1K2C: dimeric; determined by author and by software (PISA)
Molecular Components in 1K2C
Label Count Molecule
Proteins (2 molecules)
2
Protease Retropepsin
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
N-[(2R)-2-({N~5~-[amino(iminio)methyl]-L-ornithyl-L-valyl}amino)-4-methylpentyl]-L-phenylalanyl-L-alpha-glutamyl-L-alanyl-L-norleucinamideN-[(2R)-2-({N~5~-[amino(iminio)methyl]-L-ornithyl-L-valyl}amino)-4-methylpentyl]-L-phenylalanyl-L-alpha-glutamyl-L-alanyl-L-norleucinamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303