1O5B: Dissecting and Designing Inhibitor Selectivity Determinants at the S1 site Using an Artificial Ala190 Protease (Ala190 uPA)

PDB ID: 1O5BDownload
MMDB ID: 29255
PDB Deposition Date: 2003/9/9
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 1.85  Å
Source Organism:
Similar Structures:
Biological Unit for 1O5B: dimeric; determined by author and by software (PISA)
Molecular Components in 1O5B
Label Count Molecule
Proteins (2 molecules)
1
Urokinase-type Plasminogen Activator
(Gene symbol: PLAU)
Molecule annotation
1
Urokinase-type Plasminogen Activator
(Gene symbol: PLAU)
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
1
4-IODOBENZO[B]THIOPHENE-2-CARBOXAMIDINE4-IODOBENZO[B]THIOPHENE-2-CARBOXAMIDINE
2
3
CITRIC ACIDCITRIC ACID
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303