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2OO8:
Synthesis, Structural Analysis, and SAR Studies of Triazine Derivatives as Potent, Selective Tie-2 Inhibitors
PDB ID:
2OO8
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MMDB ID:
45237
PDB Deposition Date:
2007/1/25
Updated in MMDB:
2023/12
Experimental Method:
x-ray diffraction
Resolution:
2.2 Å
Source Organism:
Homo sapiens
Similar Structures:
VAST+
Download sequence data
Biological Unit for 2OO8: monomeric; determined by author
Molecular Components in 2OO8
Label
Count
Molecule
Protein (1 molecule)
X
1
Angiopoietin-1 Receptor
(Gene symbol:
TEK
)
Chemical and Non-standard biopolymers (1 molecule)
1
1
N-{3-[3-(DIMETHYLAMINO)PROPYL]-5-(TRIFLUOROMETHYL)PHENYL}-4-METHYL-3-[(3-PYRIMIDIN-4-YLPYRIDIN-2-YL)AMINO]BENZAMIDE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303