NCBI
National Center for
Biotechnology Information
Search
2UZW:
Pka Structures Of Indazole-Pyridine Series Of Akt Inhibitors
PDB ID:
2UZW
Download
MMDB ID:
46828
PDB Deposition Date:
2007/5/1
Updated in MMDB:
2007/10
Experimental Method:
x-ray diffraction
Resolution:
2.2 Å
Source Organism:
Bos taurus
Similar Structures:
VAST+
Download sequence data
Biological Unit for 2UZW: dimeric; determined by author and by software (PQS)
Molecular Components in 2UZW
Label
Count
Molecule
Proteins (2 molecules)
E
1
Camp-dependent Protein Kinase, Alpha-catalytic Subunit
(Gene symbol:
PRKACA
)
I
1
Camp-dependent Protein Kinase Inhibitor Alpha
(Gene symbol:
PKIA
)
Chemical and Non-standard biopolymers (1 molecule)
1
1
3-Pyridin-4-Yl-2,4-Dihydro-Indeno[1,2-.C.]pyrazole
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303