2C3L: Identification of a buried pocket for potent and selective inhibition of Chk1: prediction and verification

PDB ID: 2C3LDownload
MMDB ID: 36253
PDB Deposition Date: 2005/10/10
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 2.35  Å
Source Organism:
Similar Structures:
Biological Unit for 2C3L: monomeric; determined by author and by software (PQS)
Molecular Components in 2C3L
Label Count Molecule
Protein (1 molecule)
1
Serine/threonine-protein Kinase Chk1
(Gene symbol: CHEK1)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
1
3-(1H-BENZIMIDAZOL-2-YL)-1H-INDAZOLE3-(1H-BENZIMIDAZOL-2-YL)-1H-INDAZOLE
2
1
SULFATE IONSULFATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303