2OJF: Crystal structure of Protein Kinase A in complex with Pyridine-Pyrazolopyridine based inhibitors

PDB ID: 2OJFDownload
MMDB ID: 45220
PDB Deposition Date: 2007/1/12
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 2.1  Å
Source Organism:
synthetic construct▼
Similar Structures:
Biological Unit for 2OJF: dimeric; determined by author and by software (PISA)
Molecular Components in 2OJF
Label Count Molecule
Proteins (2 molecules)
1
Camp-dependent Protein Kinase, Alpha-catalytic Subunit
Molecule annotation
1
Inhibitory Peptide
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
(2S)-1-(6H-INDOL-3-YL)-3-{[5-(7H-PYRAZOLO[3,4-C]PYRIDIN-5-YL)PYRIDIN-3-YL]OXY}PROPAN-2-AMINE(2S)-1-(6H-INDOL-3-YL)-3-{[5-(7H-PYRAZOLO[3,4-C]PYRIDIN-5-YL)PYRIDIN-3-YL]OXY}PROPAN-2-AMINE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303