1N94: Aryl Tetrahydropyridine Inhbitors Of Farnesyltransferase: Glycine, Phenylalanine And Histidine Derivates

PDB ID: 1N94Download
MMDB ID: 21854
PDB Deposition Date: 2002/11/22
Updated in MMDB: 2017/11
Experimental Method:
x-ray diffraction
Resolution: 3.5  Å
Source Organism:
Similar Structures:
Biological Unit for 1N94: dimeric; determined by author and by software (PISA)
Molecular Components in 1N94
Label Count Molecule
Proteins (2 molecules)
1
Protein Farnesyltransferase Alpha Subunit
(Gene symbol: Fnta)
Molecule annotation
1
Protein Farnesyltransferase Beta Subunit
(Gene symbol: Fntb)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
1
Alpha-Hydroxyfarnesylphosphonic AcidAlpha-Hydroxyfarnesylphosphonic Acid
2
1
2-{(5-{[butyl-(2-Cyclohexyl-Ethyl)-Amino]-Methyl}-2'-Methyl-Biphenyl-2-Carbonyl)-Amino]-4-Methylsulfanyl-Butyric Acid2-{(5-{[butyl-(2-Cyclohexyl-Ethyl)-Amino]-Methyl}-2'-Methyl-Biphenyl-2-Carbonyl)-Amino]-4-Methylsulfanyl-Butyric Acid
3
1
Zinc IonZinc Ion
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303