2I0V: c-FMS tyrosine kinase in complex with a quinolone inhibitor

PDB ID: 2I0VDownload
MMDB ID: 42898
PDB Deposition Date: 2006/8/11
Updated in MMDB: 2012/12
Experimental Method:
x-ray diffraction
Resolution: 2.8  Å
Source Organism:
Similar Structures:
Biological Unit for 2I0V: monomeric; determined by author
Molecular Components in 2I0V
Label Count Molecule
Protein (1 molecule)
1
Cfms Tyrosine Kinase
(Gene symbol: CSF1R)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
1
SULFATE IONSULFATE ION
2
1
6-CHLORO-3-(3-METHYLISOXAZOL-5-YL)-4-PHENYLQUINOLIN-2(1H)-ONE6-CHLORO-3-(3-METHYLISOXAZOL-5-YL)-4-PHENYLQUINOLIN-2(1H)-ONE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303