2OH4: Crystal structure of Vegfr2 with a benzimidazole-urea inhibitor

PDB ID: 2OH4Download
MMDB ID: 59188
PDB Deposition Date: 2007/1/9
Updated in MMDB: 2023/11
Experimental Method:
x-ray diffraction
Resolution: 2.05  Å
Source Organism:
Similar Structures:
Biological Unit for 2OH4: monomeric; determined by author
Molecular Components in 2OH4
Label Count Molecule
Protein (1 molecule)
1
Vascular Endothelial Growth Factor Receptor 2
(Gene symbol: KDR)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
2
SULFATE IONSULFATE ION
2
1
METHYL (5-{4-[({[2-FLUORO-5-(TRIFLUOROMETHYL)PHENYL]AMINO}CARBONYL)AMINO]PHENOXY}-1H-BENZIMIDAZOL-2-YL)CARBAMATEMETHYL (5-{4-[({[2-FLUORO-5-(TRIFLUOROMETHYL)PHENYL]AMINO}CARBONYL)AMINO]PHENOXY}-1H-BENZIMIDAZOL-2-YL)CARBAMATE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303