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3NZ6:
Structural Analysis of Pneumocystis carinii and Human DHFR Complexes with NADPH and a Series of Five Potent 5-(omega-Carboxy(alkyloxy)Pyrido[2,3-d]pyrimidine Derivatives
PDB ID:
3NZ6
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MMDB ID:
87609
PDB Deposition Date:
2010/7/16
Updated in MMDB:
2010/12
Experimental Method:
x-ray diffraction
Resolution:
2 Å
Source Organism:
Pneumocystis carinii
Similar Structures:
VAST+
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Biological Unit for 3NZ6: monomeric; determined by author and by software (PISA)
Molecular Components in 3NZ6
Label
Count
Molecule
Protein (1 molecule)
X
1
Dihydrofolate Reductase
Chemicals and Non-standard biopolymers (2 molecules)
1
1
6-{3-[(2,4-diamino-5-methylpyrido[2,3-d]pyrimidin-6-yl)methyl]-4-methoxyphenoxy}hexanoic acid
2
1
NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303