2A9W: E. coli TS complexed with dUMP and inhibitor GA9

PDB ID: 2A9WDownload
MMDB ID: 35592
PDB Deposition Date: 2005/7/12
Updated in MMDB: 2012/11
Experimental Method:
x-ray diffraction
Resolution: 1.65  Å
Source Organism:
Similar Structures:
Biological Unit for 2A9W: dimeric; determined by author and by software (PISA)
Molecular Components in 2A9W
Label Count Molecule
Proteins (2 molecules)
2
Thymidylate Synthase
(Gene symbol: thyA)
Molecule annotation
Chemicals and Non-standard biopolymers (19 molecules)
1
6
PHOSPHATE IONPHOSPHATE ION
2
2
2'-DEOXYURIDINE 5'-MONOPHOSPHATE2'-DEOXYURIDINE 5'-MONOPHOSPHATE
3
2
3,3-BIS(3-BROMO-4-HYDROXYPHENYL)-7-CHLORO-1H,3H-BENZO[DE]ISOCHROMEN-1-ONE3,3-BIS(3-BROMO-4-HYDROXYPHENYL)-7-CHLORO-1H,3H-BENZO[DE]ISOCHROMEN-1-ONE
4
2
BETA-MERCAPTOETHANOLBETA-MERCAPTOETHANOL
5
6
GLYCEROLGLYCEROL
6
1
2-BROMOPHENOL2-BROMOPHENOL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303