2VKU: 4,4'-Dihydroxybenzophenone Mimics Sterol Substrate in the Binding Site of Sterol 14alpha-Demethylase (CYP51) in the X-ray Structure of the Complex

PDB ID: 2VKUDownload
MMDB ID: 63266
PDB Deposition Date: 2007/12/29
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 1.95  Å
Source Organism:
Similar Structures:
Biological Unit for 2VKU: monomeric; determined by author and by software (PQS)
Molecular Components in 2VKU
Label Count Molecule
Protein (1 molecule)
1
Cytochrome P450 51
Molecule annotation
Chemicals and Non-standard biopolymers (11 molecules)
1
4
bis(4-hydroxyphenyl)methanonebis(4-hydroxyphenyl)methanone
2
1
PROTOPORPHYRIN IX CONTAINING FEPROTOPORPHYRIN IX CONTAINING FE
3
6
SULFATE IONSULFATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303