NCBI
National Center for
Biotechnology Information
Search
2J6M:
Crystal structure of EGFR kinase domain in complex with AEE788
PDB ID:
2J6M
Download
MMDB ID:
45091
PDB Deposition Date:
2006/9/29
Updated in MMDB:
2023/12
Experimental Method:
x-ray diffraction
Resolution:
3.1 Å
Source Organism:
Homo sapiens
Similar Structures:
VAST+
Download sequence data
Biological Unit for 2J6M: monomeric; determined by author and by software (PQS)
Molecular Components in 2J6M
Label
Count
Molecule
Protein (1 molecule)
A
1
Epidermal Growth Factor Receptor
(Gene symbol:
EGFR
)
Chemical and Non-standard biopolymers (1 molecule)
1
1
6-{4-[(4-ETHYLPIPERAZIN-1-YL)METHYL]PHENYL}-N-[(1R)-1-PHENYLETHYL]-7H-PYRROLO[2,3-D]PYRIMIDIN-4-AMINE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303