4E49: Nucleophile recognition as an alternative inhibition mode for benzoic acid based carbonic anhydrase inhibitors

PDB ID: 4E49Download
MMDB ID: 100892
PDB Deposition Date: 2012/3/12
Updated in MMDB: 2023/11
Experimental Method:
x-ray diffraction
Resolution: 1.45  Å
Source Organism:
Similar Structures:
Biological Unit for 4E49: monomeric; determined by author and by software (PISA)
Molecular Components in 4E49
Label Count Molecule
Protein (1 molecule)
1
Carbonic Anhydrase 2
(Gene symbol: CA2)
Molecule annotation
Chemicals and Non-standard biopolymers (7 molecules)
1
1
ZINC IONZINC ION
2
1
MERCURIBENZOIC ACIDMERCURIBENZOIC ACID
3
4
RESORCINOLRESORCINOL
4
1
SULFATE IONSULFATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303