4C2V: Aurora B Kinase In Complex With The Specific Inhibitor Barasertib

PDB ID: 4C2VDownload
MMDB ID: 117781
PDB Deposition Date: 2013/8/20
Updated in MMDB: 2014/03
Experimental Method:
x-ray diffraction
Resolution: 1.49  Å
Source Organism:
Similar Structures:
Biological Unit for 4C2V: dimeric; determined by author and by software (PISA)
Molecular Components in 4C2V
Label Count Molecule
Proteins (2 molecules)
1
Aurora Kinase B-A
(Gene symbol: aurkb.L)
Molecule annotation
1
Inner Centromere Protein a
(Gene symbol: incenp.L)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
2-[5-[[7-[3-[ethyl(2-Hydroxyethyl)amino]propoxy]quinazolin-4-Yl]amino]-1h-Pyrazol-3-Yl]-N-(3-Fluorophenyl)ethanamide2-[5-[[7-[3-[ethyl(2-Hydroxyethyl)amino]propoxy]quinazolin-4-Yl]amino]-1h-Pyrazol-3-Yl]-N-(3-Fluorophenyl)ethanamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303