3EXO: Crystal structure of BACE1 bound to inhibitor

PDB ID: 3EXODownload
MMDB ID: 69430
PDB Deposition Date: 2008/10/16
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 2.1  Å
Source Organism:
Similar Structures:
Biological Unit for 3EXO: monomeric; determined by author
Molecular Components in 3EXO
Label Count Molecule
Protein (1 molecule)
1
Beta-secretase 1
(Gene symbol: BACE1)
Molecule annotation
Chemicals and Non-standard biopolymers (5 molecules)
1
3
SULFATE IONSULFATE ION
2
1
GLYCEROLGLYCEROL
3
1
N-{2-methyl-5-[(6-phenylpyrimidin-4-yl)amino]phenyl}methanesulfonamideN-{2-methyl-5-[(6-phenylpyrimidin-4-yl)amino]phenyl}methanesulfonamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303