1OPL: Structural basis for the auto-inhibition of c-Abl tyrosine kinase

PDB ID: 1OPLDownload
MMDB ID: 22813
PDB Deposition Date: 2003/3/6
Updated in MMDB: 2012/12
Experimental Method:
x-ray diffraction
Resolution: 3.42  Å
Source Organism:
Similar Structures:
Biological Unit for 1OPL: monomeric; determined by author
Molecular Components in 1OPL
Label Count Molecule
Protein (1 molecule)
1
Proto-oncogene Tyrosine-protein Kinase
(Gene symbol: ABL1)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
1
MYRISTIC ACIDMYRISTIC ACID
2
1
6-(2,6-DICHLOROPHENYL)-2-{[3-(HYDROXYMETHYL)PHENYL]AMINO}-8-METHYLPYRIDO[2,3-D]PYRIMIDIN-7(8H)-ONE6-(2,6-DICHLOROPHENYL)-2-{[3-(HYDROXYMETHYL)PHENYL]AMINO}-8-METHYLPYRIDO[2,3-D]PYRIMIDIN-7(8H)-ONE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303