3HQW: Discovery of novel inhibitors of PDE10A

PDB ID: 3HQWDownload
MMDB ID: 75811
PDB Deposition Date: 2009/6/8
Updated in MMDB: 2017/11
Experimental Method:
x-ray diffraction
Resolution: 1.7  Å
Source Organism:
Similar Structures:
Biological Unit for 3HQW: monomeric; determined by author
Molecular Components in 3HQW
Label Count Molecule
Protein (1 molecule)
1
Camp and Camp-inhibited Cgmp 3',5'-cyclic Phosphodiesterase 10A
(Gene symbol: Pde10a)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
1
ZINC IONZINC ION
2
1
MAGNESIUM IONMAGNESIUM ION
3
1
4,5-bis(4-methoxyphenyl)-2-thiophen-2-yl-1H-imidazole4,5-bis(4-methoxyphenyl)-2-thiophen-2-yl-1H-imidazole
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303