4A9R: CRYSTAL STRUCTURE OF HUMAN CHK2 IN COMPLEX WITH BENZIMIDAZOLE CARBOXAMIDE INHIBITOR

PDB ID: 4A9RDownload
MMDB ID: 103736
PDB Deposition Date: 2011/11/28
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 2.85  Å
Source Organism:
Similar Structures:
Biological Unit for 4A9R: dimeric; determined by author and by software (PISA)
Molecular Components in 4A9R
Label Count Molecule
Proteins (2 molecules)
2
Serine/threonine-protein Kinase Chk2
(Gene symbol: CHEK2)
Molecule annotation
Chemicals and Non-standard biopolymers (6 molecules)
1
2
NITRATE IONNITRATE ION
2
2
2-[4-(4-CHLOROPHENOXY)PHENYL]-1H-BENZIMIDAZOLE-6-CARBOXAMIDE2-[4-(4-CHLOROPHENOXY)PHENYL]-1H-BENZIMIDAZOLE-6-CARBOXAMIDE
3
2
1,2-ETHANEDIOL1,2-ETHANEDIOL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303