4ITH: Crystal structure of RIP1 kinase in complex with necrostatin-1 analog

PDB ID: 4ITHDownload
MMDB ID: 108335
PDB Deposition Date: 2013/1/18
Updated in MMDB: 2023/09
Experimental Method:
x-ray diffraction
Resolution: 2.25  Å
Source Organism:
Similar Structures:
Biological Unit for 4ITH: monomeric; determined by author
Molecular Components in 4ITH
Label Count Molecule
Protein (1 molecule)
1
Receptor-interacting Serine/threonine-protein Kinase 1
(Gene symbol: RIPK1)
Molecule annotation
Chemicals and Non-standard biopolymers (6 molecules)
1
4
IODIDE IONIODIDE ION
2
1
SODIUM IONSODIUM ION
3
1
(5R)-5-[(7-chloro-1H-indol-3-yl)methyl]-3-methylimidazolidine-2,4-dione(5R)-5-[(7-chloro-1H-indol-3-yl)methyl]-3-methylimidazolidine-2,4-dione
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303