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2AOT:
Histamine Methyltransferase Complexed with the Antihistamine Drug Diphenhydramine
PDB ID:
2AOT
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MMDB ID:
234617
PDB Deposition Date:
2005/8/14
Updated in MMDB:
2023/11
Experimental Method:
x-ray diffraction
Resolution:
1.9 Å
Source Organism:
Homo sapiens
Similar Structures:
VAST+
Download sequence data
Biological Unit for 2AOT: monomeric; determined by author
Molecular Components in 2AOT
Label
Count
Molecule
Protein (1 molecule)
A
1
Histamine N-methyltransferase
(Gene symbol:
HNMT
)
Chemicals and Non-standard biopolymers (2 molecules)
1
1
N-[2-(BENZHYDRYLOXY)ETHYL]-N,N-DIMETHYLAMINE
2
1
S-ADENOSYL-L-HOMOCYSTEINE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303