2Q7M: Crystal structure of human FLAP with MK-591

PDB ID: 2Q7MDownload
MMDB ID: 60202
PDB Deposition Date: 2007/6/7
Updated in MMDB: 2007/11
Experimental Method:
x-ray diffraction
Resolution: 4.25  Å
Source Organism:
Similar Structures:
Biological Unit for 2Q7M: trimeric; determined by author and by software (PISA)
Molecular Components in 2Q7M
Label Count Molecule
Proteins (3 molecules)
3
Arachidonate 5-lipoxygenase-activating Protein
(Gene symbol: ALOX5AP)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
3
3-[3-(TERT-BUTYLTHIO)-1-(4-CHLOROBENZYL)-5-(QUINOLIN-2-YLMETHOXY)-1H-INDOL-2-YL]-2,2-DIMETHYLPROPANOIC ACID3-[3-(TERT-BUTYLTHIO)-1-(4-CHLOROBENZYL)-5-(QUINOLIN-2-YLMETHOXY)-1H-INDOL-2-YL]-2,2-DIMETHYLPROPANOIC ACID
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303