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1HPS:
RATIONAL DESIGN, SYNTHESIS AND CRYSTALLOGRAPHIC ANALYSIS OF A HYDROXYETHYLENE-BASED HIV-1 PROTEASE INHIBITOR CONTAINING A HETEROCYCLIC P1'-P2' AMIDE BOND ISOSTERE
PDB ID:
1HPS
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MMDB ID:
1237
PDB Deposition Date:
1994/5/24
Updated in MMDB:
2017/12
Experimental Method:
x-ray diffraction
Resolution:
2.3 Å
Source Organism:
Human immunodeficiency virus 1
Similar Structures:
VAST+
Download sequence data
Biological Unit for 1HPS: dimeric; determined by author and by software (PISA)
Molecular Components in 1HPS
Label
Count
Molecule
Proteins (2 molecules)
A
B
2
Hiv-1 Protease
Chemicals and Non-standard biopolymers (2 molecules)
1
2
2-[(1R,3S,4S)-1-BENZYL-4-[N-(BENZYLOXYCARBONYL)-L-VALYL]AMINO-3-PHENYLPENTYL]-4(5)-(2-METHYLPROPIONYL)IMIDAZOLE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303