3K9F: Detailed structural insight into the quinolone-DNA cleavage complex of type IIA topoisomerases

PDB ID: 3K9FDownload
MMDB ID: 77723
PDB Deposition Date: 2009/10/15
Updated in MMDB: 2023/11
Experimental Method:
x-ray diffraction
Resolution: 2.9  Å
Source Organism:
synthetic construct▼
Similar Structures:
Biological Unit for 3K9F: octameric; determined by author and by software (PISA)
Molecular Components in 3K9F
Label Count Molecule
Proteins (4 molecules)
2
DNA Topoisomerase 4 Subunit a
Molecule annotation
2
DNA Topoisomerase 4 Subunit B
Molecule annotation
Nucleotides(4 molecules)
1
DNA (5'-d(*ap*cp*cp*ap*ap*gp*gp*t*cp*ap*tp*gp*ap*ap*t)-3')
Molecule annotation
1
DNA (5'-d(p*ap*gp*tp*cp*ap*tp*tp*cp*ap*tp*gp*ap*cp*cp*tp*tp*gp*gp*t)-3')
Molecule annotation
1
DNA (5'-d(*cp*tp*gp*tp*tp*tp*tp*a*cp*gp*tp*gp*cp*ap*t)-3')
Molecule annotation
1
DNA (5'-d(p*gp*ap*cp*tp*ap*tp*gp*cp*ap*cp*gp*tp*ap*ap*ap*ap*cp*ap*g)-3')
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
2
MAGNESIUM IONMAGNESIUM ION
2
2
(3S)-9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid(3S)-9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303