2VIN: Fragment-based Discovery Of Mexiletine Derivatives As Orally Bioavailable Inhibitors Of Urokinase-type Plasminogen Activator

PDB ID: 2VINDownload
MMDB ID: 62018
PDB Deposition Date: 2007/12/5
Updated in MMDB: 2017/07
Experimental Method:
x-ray diffraction
Resolution: 1.9  Å
Source Organism:
Similar Structures:
Biological Unit for 2VIN: monomeric; determined by author and by software (PQS)
Molecular Components in 2VIN
Label Count Molecule
Protein (1 molecule)
1
Urokinase-type Plasminogen Activator Chain B
(Gene symbol: PLAU)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
1
Acetate IonAcetate Ion
2
1
Sulfate IonSulfate Ion
3
1
(2r)-1-(2,6-Dimethylphenoxy)propan-2-Amine(2r)-1-(2,6-Dimethylphenoxy)propan-2-Amine
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303