1PW6: Low Micromolar Small Molecule Inhibitor of IL-2

PDB ID: 1PW6Download
MMDB ID: 26092
PDB Deposition Date: 2003/6/30
Updated in MMDB: 2017/11
Experimental Method:
x-ray diffraction
Resolution: 2.6  Å
Source Organism:
Similar Structures:
Biological Unit for 1PW6: monomeric; determined by author and by software (PISA)
Molecular Components in 1PW6
Label Count Molecule
Protein (1 molecule)
1
Interleukin-2
(Gene symbol: IL2)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
1
SULFATE IONSULFATE ION
2
2
2-CYCLOHEXYL-N-(2-{4-[5-(2,3-DICHLORO-PHENYL)-2H-PYRAZOL-3-YL]-PIPERIDIN-1-YL}-2-OXO-ETHYL)-2-GUANIDINO-ACETAMIDE2-CYCLOHEXYL-N-(2-{4-[5-(2,3-DICHLORO-PHENYL)-2H-PYRAZOL-3-YL]-PIPERIDIN-1-YL}-2-OXO-ETHYL)-2-GUANIDINO-ACETAMIDE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303