2BGD: Structure-based design of Protein Tyrosine Phosphatase-1B Inhibitors

PDB ID: 2BGDDownload
MMDB ID: 33492
PDB Deposition Date: 2004/12/21
Updated in MMDB: 2012/11
Experimental Method:
x-ray diffraction
Resolution: 2.4  Å
Source Organism:
Similar Structures:
Biological Unit for 2BGD: monomeric; determined by author and by software (PQS)
Molecular Components in 2BGD
Label Count Molecule
Protein (1 molecule)
1
Protein-tyrosine Phosphatase Non-receptor Type 1
(Gene symbol: PTPN1)
Molecule annotation
Chemicals and Non-standard biopolymers (6 molecules)
1
1
5-(4-METHOXYBIPHENYL-3-YL)-1,2,5-THIADIAZOLIDIN-3-ONE 1,1-DIOXIDE5-(4-METHOXYBIPHENYL-3-YL)-1,2,5-THIADIAZOLIDIN-3-ONE 1,1-DIOXIDE
2
3
CHLORIDE IONCHLORIDE ION
3
1
PHOSPHATE IONPHOSPHATE ION
4
1
SODIUM IONSODIUM ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303