4HTX: Crystal structure of PDE2 catalytic domain in complex with BAY60-7550

PDB ID: 4HTXDownload
MMDB ID: 112989
PDB Deposition Date: 2012/11/2
Updated in MMDB: 2014/12
Experimental Method:
x-ray diffraction
Resolution: 1.9  Å
Source Organism:
Similar Structures:
Biological Unit for 4HTX: dimeric; determined by author and by software (PISA)
Molecular Components in 4HTX
Label Count Molecule
Proteins (2 molecules)
2
Cgmp-dependent 3',5'-cyclic Phosphodiesterase
(Gene symbol: PDE2A)
Molecule annotation
Chemicals and Non-standard biopolymers (6 molecules)
1
2
ZINC IONZINC ION
2
2
MAGNESIUM IONMAGNESIUM ION
3
2
2-(3,4-dimethoxybenzyl)-7-[(2R,3R)-2-hydroxy-6-phenylhexan-3-yl]-5-methylimidazo[5,1-f][1,2,4]triazin-4(3H)-one2-(3,4-dimethoxybenzyl)-7-[(2R,3R)-2-hydroxy-6-phenylhexan-3-yl]-5-methylimidazo[5,1-f][1,2,4]triazin-4(3H)-one
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303