1Z6J: Crystal Structure of a ternary complex of Factor VIIa/Tissue Factor/Pyrazinone Inhibitor

PDB ID: 1Z6JDownload
MMDB ID: 177840
PDB Deposition Date: 2005/3/22
Updated in MMDB: 2021/10
Experimental Method:
x-ray diffraction
Resolution: 2  Å
Source Organism:
Similar Structures:
Biological Unit for 1Z6J: trimeric; determined by author and by software (PISA)
Molecular Components in 1Z6J
Label Count Molecule
Proteins (3 molecules)
1
Coagulation Factor VII
(Gene symbol: F7)
Molecule annotation
1
Coagulation Factor VII
(Gene symbol: F7)
Molecule annotation
1
Tissue Factor
(Gene symbol: F3)
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
2
CALCIUM IONCALCIUM ION
2
1
MAGNESIUM IONMAGNESIUM ION
3
1
5-[AMINO(IMINO)METHYL]-2-[({[6-[3-AMINO-5-({[(1R)-1-METHYLPROPYL]AMINO}CARBONYL)PHENYL]-3-(ISOPROPYLAMINO)-2-OXOPYRAZIN-1(2H)-YL]ACETYL}AMINO)METHYL]-N-PYRIDIN-4-YLBENZAMIDE5-[AMINO(IMINO)METHYL]-2-[({[6-[3-AMINO-5-({[(1R)-1-METHYLPROPYL]AMINO}CARBONYL)PHENYL]-3-(ISOPROPYLAMINO)-2-OXOPYRAZIN-1(2H)-YL]ACETYL}AMINO)METHYL]-N-PYRIDIN-4-YLBENZAMIDE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303