2VGO: Crystal structure of Aurora B kinase in complex with Reversine inhibitor

PDB ID: 2VGODownload
MMDB ID: 67574
PDB Deposition Date: 2007/11/15
Updated in MMDB: 2022/11
Experimental Method:
x-ray diffraction
Resolution: 1.7  Å
Source Organism:
Similar Structures:
Biological Unit for 2VGO: dimeric; determined by software (PQS)
Molecular Components in 2VGO
Label Count Molecule
Proteins (2 molecules)
1
Serine/threonine-protein Kinase 12-a
(Gene symbol: aurkb.L)
Molecule annotation
1
Inner Centromere Protein a
(Gene symbol: incenp.L)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
N~6~-cyclohexyl-N~2~-(4-morpholin-4-ylphenyl)-9H-purine-2,6-diamineN~6~-cyclohexyl-N~2~-(4-morpholin-4-ylphenyl)-9H-purine-2,6-diamine
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303