NCBI
National Center for
Biotechnology Information
Search
3N8W:
Crystal Structure of R120Q/Native Cyclooxygenase-1 Heterodimer mutant in complex with Flurbiprofen
PDB ID:
3N8W
Download
MMDB ID:
83675
PDB Deposition Date:
2010/5/28
Updated in MMDB:
2023/09
Experimental Method:
x-ray diffraction
Resolution:
2.75 Å
Source Organism:
Ovis aries
Similar Structures:
VAST+
Download sequence data
Biological Unit for 3N8W: dimeric; determined by author and by software (PISA)
Molecular Components in 3N8W
Label
Count
Molecule
Proteins (2 molecules)
A
1
Prostaglandin G/H Synthase 1
(Gene symbol:
PTGS1
)
B
1
Prostaglandin G/H Synthase 1
(Gene symbol:
PTGS1
)
Chemicals and Non-standard biopolymers (24 molecules)
1
8
2-acetamido-2-deoxy-beta-D-glucopyranose
2
4
2-acetamido-2-deoxy-alpha-D-glucopyranose
3
3
beta-D-mannopyranose
4
3
alpha-D-mannopyranose
5
2
PROTOPORPHYRIN IX CONTAINING FE
6
1
FLURBIPROFEN
7
3
octyl beta-D-glucopyranoside
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303