4I87: Crystal structure of TTR variant I84S in complex with CHF5074 at acidic pH

PDB ID: 4I87Download
MMDB ID: 111071
PDB Deposition Date: 2012/12/3
Updated in MMDB: 2023/09
Experimental Method:
x-ray diffraction
Resolution: 1.69  Å
Source Organism:
Similar Structures:
Biological Unit for 4I87: tetrameric; determined by author and by software (PISA)
Molecular Components in 4I87
Label Count Molecule
Proteins (4 molecules)
4
Transthyretin
(Gene symbol: TTR)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
2
1-(3',4'-dichloro-2-fluorobiphenyl-4-yl)cyclopropanecarboxylic acid1-(3',4'-dichloro-2-fluorobiphenyl-4-yl)cyclopropanecarboxylic acid
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303