2FES: Orally active thrombin inhibitors

PDB ID: 2FESDownload
MMDB ID: 39267
PDB Deposition Date: 2005/12/16
Updated in MMDB: 2012/11
Experimental Method:
x-ray diffraction
Resolution: 2.42  Å
Source Organism:
Homo sapiens▼
Similar Structures:
Biological Unit for 2FES: trimeric; determined by author and by software (PISA)
Molecular Components in 2FES
Label Count Molecule
Proteins (3 molecules)
1
Thrombin Light Chain
Molecule annotation
1
Thrombin Heavy Chain
Molecule annotation
1
Decapeptide Hirudin Analogue
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
N-(CARBOXYMETHYL)-3-CYCLOHEXYL-D-ALANYL-N-({5-[(E)-AMINO(IMINO)METHYL]THIEN-2-YL}METHYL)-L-PROLINAMIDEN-(CARBOXYMETHYL)-3-CYCLOHEXYL-D-ALANYL-N-({5-[(E)-AMINO(IMINO)METHYL]THIEN-2-YL}METHYL)-L-PROLINAMIDE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303