3VW8: Crystal structure of human c-Met kinase domain with its inhibitor

PDB ID: 3VW8Download
MMDB ID: 112550
PDB Deposition Date: 2012/8/8
Updated in MMDB: 2013/12
Experimental Method:
x-ray diffraction
Resolution: 2.1  Å
Source Organism:
Similar Structures:
Biological Unit for 3VW8: monomeric; determined by author and by software (PISA)
Molecular Components in 3VW8
Label Count Molecule
Protein (1 molecule)
1
Hepatocyte Growth Factor Receptor
(Gene symbol: MET)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
1
N-({4-[(6,7-dimethoxyquinolin-4-yl)oxy]phenyl}carbamothioyl)-2-phenylacetamide (Link to PubChem not yet available)N-({4-[(6,7-dimethoxyquinolin-4-yl)oxy]phenyl}carbamothioyl)-2-phenylacetamide
2
1
CHLORIDE ION (Link to PubChem not yet available)CHLORIDE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303