4N9C: Fragment-based Design of 3-Aminopyridine-derived Amides as Potent Inhibitors of Human Nicotinamide Phosphoribosyltransferase (NAMPT)

PDB ID: 4N9CDownload
MMDB ID: 117687
PDB Deposition Date: 2013/10/20
Updated in MMDB: 2024/03
Experimental Method:
x-ray diffraction
Resolution: 1.751  Å
Source Organism:
Similar Structures:
Biological Unit for 4N9C: dimeric; determined by author and by software (PISA)
Molecular Components in 4N9C
Label Count Molecule
Proteins (2 molecules)
2
Nicotinamide Phosphoribosyltransferase
(Gene symbol: NAMPT)
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
2
5-nitro-1H-benzimidazole5-nitro-1H-benzimidazole
2
2
PHOSPHATE IONPHOSPHATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303