1YOU: Crystal structure of the catalytic domain of MMP-13 complexed with a potent pyrimidinetrione inhibitor

PDB ID: 1YOUDownload
MMDB ID: 32529
PDB Deposition Date: 2005/1/28
Updated in MMDB: 2012/11
Experimental Method:
x-ray diffraction
Resolution: 2.3  Å
Source Organism:
Similar Structures:
Biological Unit for 1YOU: monomeric; determined by author
Molecular Components in 1YOU
Label Count Molecule
Protein (1 molecule)
1
Collagenase 3
(Gene symbol: MMP13)
Molecule annotation
Chemicals and Non-standard biopolymers (6 molecules)
1
2
ZINC IONZINC ION
2
1
CALCIUM IONCALCIUM ION
3
2
SULFATE IONSULFATE ION
4
1
5-(2-ETHOXYETHYL)-5-[4-(4-FLUOROPHENOXY)PHENOXY]PYRIMIDINE-2,4,6(1H,3H,5H)-TRIONE5-(2-ETHOXYETHYL)-5-[4-(4-FLUOROPHENOXY)PHENOXY]PYRIMIDINE-2,4,6(1H,3H,5H)-TRIONE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303