2VA7: X-ray crystal structure of beta secretase complexed with compound 27

PDB ID: 2VA7Download
MMDB ID: 60623
PDB Deposition Date: 2007/8/30
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 2.2  Å
Source Organism:
Similar Structures:
Biological Unit for 2VA7: dimeric; determined by author and by software (PQS)
Molecular Components in 2VA7
Label Count Molecule
Proteins (2 molecules)
2
Beta-secretase 1 .
(Gene symbol: BACE1)
Molecule annotation
Chemicals and Non-standard biopolymers (8 molecules)
1
6
IODIDE IONIODIDE ION
2
2
(6R)-2-amino-6-[2-(3'-methoxybiphenyl-3-yl)ethyl]-3,6-dimethyl-5,6-dihydropyrimidin-4(3H)-one(6R)-2-amino-6-[2-(3'-methoxybiphenyl-3-yl)ethyl]-3,6-dimethyl-5,6-dihydropyrimidin-4(3H)-one
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303