2ZA5: Crystal Structure of human tryptase with potent non-peptide inhibitor

PDB ID: 2ZA5Download
MMDB ID: 62711
PDB Deposition Date: 2007/10/2
Updated in MMDB: 2023/11
Experimental Method:
x-ray diffraction
Resolution: 2.3  Å
Source Organism:
Similar Structures:
Biological Unit for 2ZA5: tetrameric; determined by author and by software (PISA)
Molecular Components in 2ZA5
Label Count Molecule
Proteins (4 molecules)
4
Tryptase Beta 2
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
4
(5-(aminomethyl)-2H-spiro[benzofuran-3,4'-piperidine]-1'-yl)(5-(phenylethynyl)furan-2-yl)methanone(5-(aminomethyl)-2H-spiro[benzofuran-3,4'-piperidine]-1'-yl)(5-(phenylethynyl)furan-2-yl)methanone
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303